Associate Scientist - Analytical & Bioanalytical Mass Spectrometry (ABMS)

About the role

The Analytical and Biological Mass Spectrometry Group (ABMS) at Regeneron Pharmaceuticals, Inc., located in Tarrytown, NY, is seeking an Associate Scientist to join their team. The role involves developing and optimizing liquid chromatography coupled to mass spectrometry (LC-MS) related methods for the enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates, and monoclonal antibodies (mAbs).

Responsibilities

• Develop and optimize LC-MS related methods for the enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates, and monoclonal antibodies (mAbs)
• Perform analytical testing and sample preparation of siRNA/oligonucleotides with a focus on chromatographic fractionation, LC, LC-MS, solid phase extraction (SPE), hybridization-capture, and other mass spectrometry related methods
• Independently conduct sample preparation and LC-MS analyses in compliance with Standard Operating Procedures (SOPs) or drafted protocols, and document experimental procedures and results in electronic laboratory notebook (ELN)

Requirements

• Bachelor's Degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field
• 0-3 years of relevant hands-on laboratory experience in analytical chemistry or bioanalytical sciences
• Strong hands-on experience with liquid chromatography (such as reversed-phase, size-exclusion, ion exchange chromatography)
• Experience with various types of biological matrices is a plus
• Experience with fractionation, solid phase extraction, and/or hybridization techniques is particularly valuable

Qualifications

• Mentally flexible and adaptable to changing priorities in a fast-paced environment
• An excellent team player who can follow directions while also contributing innovative solutions
• A growth mindset and eagerness to tackle new challenges and learn from experiences
• Interest in genetic medicines and development of RNA-based therapies

Skills

• Excellent chromatography skills
• Ability to optimize separation methods independently
• Comfortable working independently after initial guidance
• Effective communication about technical challenges and results

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on the country of employment: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

Pay

$93,900.00 - $153,300.00 annually

Schedule

Full time