Visiting Grad Student

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine—along with the Duke University School of Nursing and Duke University Health System—comprise Duke Health, a world-class academic medical center.

The Lan Lab is dedicated to researching how cancer cells respond to DNA damage through DNA repair mechanisms and developing innovative strategies to target these pathways in cancer therapy. Significant contributions include uncovering the critical role of PARP in DNA repair, leading to successful applications of PARP inhibitors in the treatment of breast, ovarian, and other types of cancer. The lab studies how DNA responds to oxidative damage at specific chromosomal locations, advancing understanding of DNA damage response in different chromosomal environments. Recent investigations have revealed a novel mRNA and R-loop-dependent DNA repair pathway that acts as a protective mechanism for the transcribed regions of the genome, introducing a new paradigm in DNA repair research.

About the role

The incumbent will work on a research project focused on targeting R-loops in glioblastoma (GBM). They will conduct key experiments essential for completing the study and submit the resulting manuscript to Nature Communications.

Requirements

• BA or BS
• Student must be engaged in graduate research sponsored by a Duke faculty member

Benefits

• Health insurance plans
• Generous paid time off
• Retirement programs with employer contributions
• Tuition assistance for employees and their children