Vice President, Biometrics

About the role

Located in Cambridge, MA and reporting to the Chief of Staff to the Chief Medical Officer, the Vice President, Biometrics will lead Hemab’s biostatistics, statistical programming, and data science functions, shaping clinical development strategy and ensuring rigorous evidence generation across the portfolio.

Responsibilities

• Set and own Hemab’s Biometrics strategy across the portfolio, ensuring statistical and data approaches answer patient‑, development‑, regulatory‑, and value‑focused questions.
• Shape clinical development from early stage through registration, bringing statistical judgement to trial design, endpoints, estimands, evidence generation, and benefit‑risk decisions.
• Lead statistical strategy for clinical development, finding rigorous, pragmatic approaches for small patient populations.
• Serve as Hemab’s senior statistical voice with health authorities, shaping regulatory interactions and submissions and representing evidence when challenged.
• Lead and grow Biostatistics, Statistical Programming, and Data Science teams, building capabilities as the portfolio scales.
• Strengthen portfolio decision‑making, helping teams distinguish signal from noise, understand uncertainty, and make timely evidence‑grounded decisions.
• Partner across Clinical Development, Clinical Operations, Regulatory Affairs, Clinical Pharmacology, and Medical Affairs, providing an independent quantitative perspective.
• Advance quantitative science at Hemab, including adaptive and Bayesian methods, modeling, simulation, and emerging data‑science approaches.
• Shape how Hemab evaluates and adopts new technologies (e.g., AI), setting standards for responsible use in trial design, analysis, and evidence generation.
• Develop and embed processes and ways of working for Hemab Biometrics from study start‑up through analysis, database lock, and submission‑ready deliverables.
• Create frameworks for statistical rigor, data quality, and regulatory readiness, including oversight of CROs and specialist partners.

Requirements

• PhD in Statistics/Biostatistics with 12+ years pharmaceutical/biotech industry experience, OR Master's degree in Statistics/Biostatistics with 15+ years pharmaceutical/biotech industry experience.
• Significant leadership experience in Biostatistics/Biometrics within biotech or pharmaceutical clinical development, with accountability across multiple development programs.
• Deep statistical expertise and a track record of shaping clinical development strategy, not just executing analyses.
• Experience across multiple stages of clinical development, including late‑stage development and regulatory submissions.
• Direct experience developing statistical strategy for and engaging with major health authorities.
• Experience leading teams and multidisciplinary Biometrics capabilities, with oversight across Biostatistics, Statistical Programming, and Data Science.
• Ability to turn complex statistical evidence into clear, decision‑useful recommendations for clinical teams, senior leaders, and non‑statistical audiences.
• Excellent communicator and influencer, attuned to stakeholder needs and able to influence effectively.

Qualifications

• Rare‑disease, hematology, or coagulation development experience (nice to have).
• Experience designing studies for small patient populations where conventional approaches may not be sufficient.
• Deep experience with adaptive designs, Bayesian methods, modeling, and simulation.
• Experience scaling Biometrics capabilities in a growing clinical‑stage biotech.

Skills

• Problem‑solving mindset: tackles obstacles directly, seeks help with humility, avoids ego, and partners across disciplines.
• Strong communication and influencing abilities.
• Leadership and team‑building expertise.
• Strategic thinking and ability to set portfolio‑level Biometrics strategy.