UNIV - Research Specialist II - Department of Pharmacology and Immunology

Job Duties

• Sample organization and preparation. Familiarity with randomization approaches to pre-prep sample organization using clinical characteristics and sample preparation for mass spectrometry studies.
  • Automated enzymatic digestion, buffer preparation, application of antibody tags in a clean environment.
  • Capable of reaching milestone achievements.
• Data analysis. Collaboration with multiple labs for image data processing and data modeling by simulators. Familiarity with verification and validation procedures to ensure appropriate modeling.
  • Use of a variety of programs such as Excel, GraphPad, ImageJ and SPSS, Python and R to report data.
  • Learn and communicate new proteomic software for peptide clustering and proteomic reporting.
• High throughput assays.
• Training students or visiting scholars in laboratory workflows surrounding proteomics.
• Maintain laboratory equipment. System suitability tests on equipment used in each part of the study and record findings, troubleshooting when necessary.
• Keep the lab safe, clean and compliant by following PPE and MUSC guidelines for safety in the laboratory.

Qualifications

• A bachelor's degree in chemistry, biology, or other natural, life or health care science and one year work experience directly related to the assigned research area.
• Experience in one or more of the following desired: proteomics, chromatography, mass spectrometry, tandem mass spectrometry, trapped ion mobility, orbitrap, isotopic labeling, DIA, DDA, post-translational modifications.

Physical Requirements

• Ability to perform job functions in an upright position (Frequent).
• Ability to perform job functions in a seated position (Continuous).
• Ability to perform job functions while walking/mobile (Frequent).
• Ability to climb, using step stool (Infrequent).
• Ability to work in temperature extremes (32° F to 100° F) when required due to assignments in cold rooms and/or foreign countries (Infrequent).
• Ability to work in confined/cramped spaces (Continuous).
• Ability to bend at the waist (Frequent).
• Ability to twist at the waist (Frequent).
• Ability to fully use both hands/arms (Continuous).
• Ability to perform repetitive motions with hands/wrists/elbows and shoulders (Frequent).
• Ability to fully use both legs (Frequent).
• Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions (Frequent).
• Ability to maintain good olfactory sensory function/distinction (Continuous).
• Ability to lift materials up to 20 lbs., unassisted (Infrequent).
• Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted (Frequent).
• Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted (Infrequent).
• Ability to lift file boxes, from floor level to counter tops, unassisted (Frequent).
• Ability to push/pull file boxes from one location to another at floor level (Frequent).
• Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted (Frequent).
• Ability to perform gross motor functions with frequent fine motor movements (Continuous).
• Ability to maintain 20/40 vision, corrected, in one eye or with both eyes (Continuous).
• Ability to match or discriminate between colors, normally (Continuous).
• Ability to hear and recognize various alarms emitting from work area systems (Continuous).
• Ability to hear and/or understand conversations (Continuous).
• Ability to work in a darkroom for processing film, etc. (Continuous).
• Ability to be qualified physically for respirator use, initially and annually (Continuous).

Additional New Requirements

• Ability to work rotating shifts as required.
• Ability to work overtime as required.
• Ability to learn and use new processes, tools and equipment as required.