Target Discovery – Target Validation Associate Scientist

Responsibilities

• Design and execute discovery‑stage research to identify and validate novel immunotherapy targets using primary human samples and cell lines.
• Engage in processing of primary samples including tissue dissociation, antibody staining, and flow sorting/cytometry.
• Design, optimize, and perform cell line screening workflows using flow cytometry, ELISA, Western, and other methods.
• Collaborate closely with computational and translational teams to interpret findings and advance candidate targets into development.
• Independently conduct experiments; maintain detailed records of experiments and outcomes; and work in collaboration with other team members.
• Present data and strategic updates to internal teams and external collaborators; contribute to scientific direction and project planning.
• Contribute to the presentation of findings (slide deck, white paper, publication) as needed.

Qualifications, Skills, Knowledge & Abilities

B.S. or M.S. in immunology, molecular/cell biology, genomics, bioengineering, or a related field with 4+ years (B.S.) or 2+ years (M.S.) of hands‑on, progressively independent industry experience in target discovery and validation or related research. Proven track record of independently designing, executing, and analyzing complex biological experiments. Excellent communication and collaboration skills with a demonstrated ability to work as part of a team.

• Primary cell and tissue processing (e.g., mammalian cell culture, tissue dissociation, and staining)
• Advanced flow cytometry and cell sorting (e.g., multiparameter panels, spectral flow cytometry)
• Ability to analyze and visualize data using common bioinformatics tools (e.g., FlowJo, Prism, R, or Python)
• Experience using electronic notebooks (e.g., Benchling)