Sr. Research Associate, Process Development Upstream

About the role

Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes. The Sr. Research Associate in Process Development – Upstream will develop and optimize scalable cell culture processes and transfer the process to Avid Manufacturing. The role also involves maintaining production equipment, researching and implementing new methods and technologies, and supervising junior staff.

Responsibilities

• Develop and optimize mammalian cell culture processes, including recombinant protein production, cell adaptation to suspension or serum-free conditions, and media/feed screening.
• Grow and maintain cells in shake flasks, wave and stirred tank bioreactors; perform seed train development, production bioreactor inoculation, maintenance, sampling, and feeding; conduct cell culture harvest and clarification.
• Work with various mammalian cell lines (e.g., CHO-GS, CHO-DG44, CHO-M, CHO-S, NSO, HEK) using aseptic techniques and apply knowledge of metabolic, physical, and mechanical parameters affecting cell growth and protein production.
• Prepare cell culture media and feed formulations from scratch; operate, troubleshoot, and maintain cell culture equipment such as bioreactors and analyzers.
• Scale up and tech transfer cell culture and harvest processes to the Manufacturing department; provide technical support to Process Development and Manufacturing teams.
• Lead studies to optimize/develop cell culture conditions/processes and serve as the scientific lead on client projects.
• Analyze growth, production, and nutrient usage data; create data spreadsheets and graphs in Excel or JMP; document data and findings for traceability and regulatory requirements; write technical and summary reports; generate slide decks; and communicate findings in scientific discussions.
• Recommend alternatives, research new methods and techniques, and proactively seek solutions to problems; supervise and train junior cell culture team members.
• Work with minimal supervision on projects of moderate to complex scope.

Minimum Qualifications

• Bachelor’s degree in the biological or physical sciences with a minimum of 4–5 years of relevant experience.
• Demonstrated working knowledge of scientific principles and proficiency in the use of scientific laboratory techniques, equipment, and materials.
• Experience in process validation and conducting process validation studies.

Compensation

Competitive compensation package including base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off. The compensation range for this role is $72,800 – $91,000 annually, depending on experience and qualifications. Opportunities for career growth and development are available in a supportive and inclusive work environment.

Who you are

• Team player with a "bring it!" attitude and a positive, can-do approach.
• Strong written and verbal communication skills with clarity and confidence.
• Exceptional multitasking skills and unparalleled attention to detail.
• Skilled at building relationships with team members, clients, vendors, and suppliers.

Physical Demands & Work Environment

This role involves a blend of regular activities such as sitting, standing, and walking, with occasional physically engaging tasks like lifting objects up to 20 pounds. The work environment may expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels. Reasonable accommodations are available. Visual acuity, including close, distance, and color vision, is essential for daily tasks.