Research Associate, Upstream Process Development

About the role

Krystal Biotech, Inc. is seeking a highly motivated and innovative Research Associate to support multidisciplinary efforts in Upstream Process Development. The Research Associate will support process development initiatives by conducting experiments related to the characterization, optimization, and scale-up of viral vector production. They will support the tech transfer of developed processes to the Manufacturing team.

Responsibilities

• Set up and operate bench scale bioreactors under the guidance of senior staff
• Perform mammalian cell culture using aseptic techniques
• Prepare buffers and media, maintain equipment, and order supplies to ensure the lab runs smoothly
• Provide technical support in the lab through equipment maintenance and troubleshooting
• Participate in study design and process development brainstorming sessions
• Design scientifically sound experiments and record data accurately in electronic lab notebooks
• Adhere to safety guidelines and maintain a clean and orderly lab environment
• Analyze experimental data and effectively communicate findings with manager and rest of process development team
• Interact with cross-functional teams (manufacturing, MSAT, etc.) to identify and solve problems encountered during process scale-up

Requirements

• Bachelor’s Degree in Biomedical Engineering, Chemical Engineering, Bioengineering or a related scientific discipline.
• Some understanding in one or more of the following areas: aseptic technique, mammalian cell culture, bioreactor technology, cell biology, and/or virology
• Familiarity with bioreactor operation and upstream processing is a plus
• Familiarity with lab automation or basic coding is a plus
• High capability of multitasking in a fast-paced team-oriented environment
• Excellent oral and written communication skills