Sr. Manager, Clinical Operations

About the Role

The Sr. Manager, Clinical Operations will drive the operational execution and strategic management of high-impact alliances central to 10x Genomics’ effort to advance future diagnostic applications for single cell and spatial technologies. This role reports to the Director, Business Development and Strategic Partnerships.

Responsibilities

Clinical Operations and Study Execution

• Study Execution: Manage the operational execution of large-scale, longitudinal clinical research studies according to established agreements with academic institutions.
• Timeline & Risk: Own and drive clinical research study timelines, deliverables, and operational plans ensuring adherence to sampling schedules; identify operational risks regarding enrollment, setup, or logistics early, implementing mitigation strategies to maintain study integrity.
• Sample Logistics & Chain of Custody: Establish and enforce auditable procedures for sample collection, tracking, and chain of custody, ensuring compliant transport from clinical sites to 10x Genomics laboratory.
• Budget & Resource Oversight: Manage the study budgets, including the oversight of reimbursement, equipment provisioning, and consumables provided to partner sites.
• Regulatory & Quality Compliance: Ensure all study activities comply with IRB protocols, patient consent requirements, and GCLP/CLIA standards where applicable.

Academic Collaboration Management

• Portfolio Management: Manage a diverse, high-value portfolio of academic collaborations and strategic partnerships to ensure all projects and agreements track toward established milestones and outcomes.
• Stakeholder Management: Act as the primary liaison between internal teams and key stakeholders at relevant academic institutions and industry partners to foster strong, collaborative relationships that drive engagement and performance.
• Contract Lifecycle Management: Oversee compliance with contractual obligations, milestones, and deliverables, working closely with Legal, Finance, and Business Development to drive contract amendments or renewals as needed.

Requirements

• An Advanced degree (M.S., PharmD, Ph.D., M.B.A.) in a Life Science, Clinical, or related field is required.
• 8+ years of relevant industry experience with 4-5 years of experience in Clinical Operations within the diagnostics, biotechnology, or pharmaceutical industry.
• Direct experience managing research studies involving large numbers of patient samples and complex molecular testing or biomarkers.
• Deep understanding of clinical study execution, site management, and the complexities of clinical sample logistics and chain of custody.
• Preferably, experience in managing high-value strategic alliances and driving value through the successful execution of collaborative research, development, or commercialization agreements.
• Demonstrated ability to manage competing priorities, swiftly resolve complex operational problems, and drive tangible results.

Preferred Skills and Experience

• Thrives in a fast-paced environment with a ‘roll up your sleeves and get it done’ mentality.
• Excellent at communicating, organizing, and leading external stakeholders and internal cross-functional teams to achieve desired outcomes.
• Comfortable leading through ambiguity and change; focusing on finding practical solutions and driving clarity to maintain program momentum.
• Exceptional at building strong, collaborative relationships with diverse stakeholders, including external investigators, and internal technical and executive teams.
• Willing to travel up to 25% for site visits, investigator meetings, and external partner engagement.
• Startup or small biotech experience.
• Familiarity with CLIA/CAP standards as they relate to samples sent to a centralized testing laboratory is preferred.

Pay

Base pay range for this full-time position: $173,100—$234,100 USD. The actual base pay will depend on skills, qualifications, and experience. This role is also eligible for 10x’s equity grants, comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program.

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides.