Senior Upstream Process Engineer, Commercial - BPG

About the role

Thermo Fisher Scientific's Bioproduction Group (BPG) is seeking a Senior Upstream Process Engineer (Commercial) to serve as a technical leader at the intersection of engineering, sales, and customer solutions. This role is responsible for defining and shaping upstream bioprocess solutions for capital projects supporting drug substance manufacturing, with a focus on cell culture media, bioreactors, and automation systems.

Key responsibilities

• Lead upstream process design, including PFDs, P&IDs, balances, and equipment specs
• Develop scalable solutions for media prep and bioreactor-based manufacturing with automation
• Ensure compliance with cGMP and global regulatory standards
• Lead FEL/FEED efforts, translating customer needs into defined scopes
• Develop costed proposals with scope, assumptions, risks, and exclusions
• Support CAPEX estimates aligned with commercial and margin goals
• Serve as primary technical contact for customers and project teams
• Lead design reviews, technical discussions, and executive presentations
• Collaborate cross-functionally across sales, engineering, and global teams
• Contribute to technical marketing (white papers, webinars, presentations)
• Represent Thermo Fisher at industry events to promote bioproduction solutions
• Ensure smooth handoff to execution teams with clear scope and continuity
• Provide technical guidance during early project phases as needed

Qualifications

• Bachelor's degree in Chemical Engineering, Biochemical Engineering, Mechanical Engineering, or related technical field required; Master's or PhD preferred
• 8+ years of experience in process engineering or bioprocess system design within the biopharma or life sciences industry
• Strong expertise in upstream bioprocessing, including cell culture, media preparation, and single-use technologies
• Experience with capital equipment projects and development of complex engineering proposals
• Demonstrated ability to lead front-end engineering, scope definition, and technical solution development
• Familiarity with automation platforms (e.g., DeltaV, PLC/SCADA systems) and integration within bioprocess facilities preferred
• Strong understanding of cGMP and global regulatory frameworks (FDA, EMA, ICH)
• Proven ability to influence and collaborate across cross-functional and global teams
• Excellent communication and presentation skills, with experience engaging customer stakeholders and executive audiences
• Ability to manage multiple priorities in a fast-paced, customer-driven environment

Schedule

• Standard work schedule (Monday–Friday)
• Remote role
• Global travel estimated up to 25% of the time, independently to customer sites, factories, trade shows, and meetings

Pay & benefits

• Salary range estimated for this position based in Massachusetts: $120,000–$210,000
• Eligible for a variable annual bonus based on company, team, and/or individual performance
• Choice of national medical and dental plans, and a national vision plan, including health incentive programs
• Employee assistance and family support programs, including commuter benefits and tuition reimbursement
• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability
• Competitive 401(k) U.S. retirement savings plan
• Employees Stock Purchase Plan (ESPP) offering eligible colleagues the opportunity to purchase company stock at a discount