Senior Staff Scientist (Transgenic Animal and Genome Editing facility)

Primary location: Cincinnati, OH (United States of America). Full-time position, 40 hours per week, day shift.

About the role

The Transgenic Animal and Genome Editing facility (TAGE) is looking for an experienced scientist to assist in running the operations of the facility.

Responsibilities

• Initiate, direct, and execute scientific research pertaining to a specific field of study; investigate the feasibility of applying scientific principles and concepts to solve problems.
• Work on complex problems requiring in-depth evaluation of various factors, applying expertise and broad knowledge of principles, theories, and standard scientific/research protocols.
• Create formal networks with key decision makers and use professional concepts to solve complex problems in creative and effective ways.
• Exercise judgment within broadly defined practices and policies in selecting methods, techniques, and evaluation criteria for obtaining results.
• Manage lab administration (IRB/IACUC/biosafety) and oversee divisional or institutional core facilities, including managing and/or providing training for instrumentation.
• Research and improve current methods, evaluate innovative techniques, design and perform experiments, and record data according to research protocol.
• Independently reproduce, evaluate, research, and improve techniques currently used; adapt new methods to existing procedures.
• Draft, write, and edit scientific reports, papers, journal articles, and abstracts; present at local, national, and international scientific meetings.
• Partner with Principal Investigators (PI) to review papers for journals; demonstrate continued productivity with multiple publications (minimum 10 as an example), including at least one first authorship paper and multiple first or co-senior author papers.
• Lead and contribute to grant writing and applications; serve as Co-Investigator on grants.
• Assist in preparing, writing, and maintaining fiscal budgets; monitor expenditures, prepare capital expenditure requests, and track funding.
• Supervise junior lab members and trainees, including direct reports; serve as the contact for resolution of complex issues, provide education, guidance, and work direction.
• Provide input and feedback to managers on hiring decisions, professional development, and performance management.
• Lead research programs or research teams within a lab and serve as leaders of divisional cores; interface with various departments as an expert in the line of research.
• Initiate and lead teaching, providing lectures and lab classes; advise PI and other stakeholders as needed.
• Train and supervise the work of other laboratory personnel; maintain an integral role in laboratory meetings, presentations, and publications.
• Present information on research and laboratory work at laboratory meetings, journal clubs, and seminars.
• Maintain accurate and detailed records of all laboratory work and experiments; develop, set up, and verify new procedures in the laboratory.
• Standardize and establish new published procedures; evaluate innovative techniques and develop new assays and protocols.
• Discuss relevant insights about experimental results with the Director and provide useful recommendations and analysis.
• Troubleshoot and correct erroneous results or problems with laboratory equipment; maintain and repair equipment and monitor proper use by personnel.
• Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks.
• Act independently with limited supervision to determine methods and procedures on new assignments.

Qualifications

• Proven ability to understand and execute difficult concepts.
• Consistent or increasing trajectory of accomplishment in technical proficiency, scientific creativity, collaboration with others, and independent thought.
• Productivity as measured by continued authorship on papers (e.g., lab, field of research, and paper impact), with first authorship weighted more heavily or co-senior/co-corresponding authorship.
• Experience as Co-Investigator or writing grant applications, including writing the majority of grant applications with PI guidance.
• Increased responsibility in division and lab management, leadership within the lab, and divisional responsibility.
• Important contributions to scientific literature and conferences.

About Us

At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose.

• Recognized by U.S. News & World Report as a top 10 best Children's Hospitals in the nation for more than 15 years.
• Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) funding.
• Recognized as one of America’s Best Large Employers (2025) and America’s Best Employers for New Grads (2025).
• Named one of the nation's America’s Most Innovative Companies by Fortune.
• A Leading Disability Employer as noted by the National Organization on Disability.
• Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC).
• We embrace innovation and support the responsible use of artificial intelligence to create space for new ideas, better outcomes, and a stronger future.