Senior Scientist, Gene Delivery and Editing Process Development

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. Job Description The Senior Scientist will join the Gene Delivery and Editing Process Development (GDEPD) organization supporting process development, production, and characterization of viral vectors, which are critical to generating BMS’s groundbreaking cell therapies. The candidate will help drive next-generation viral vector platform development and support the advancement of clinical programs. Responsibilities Design, execute, and troubleshoot upstream development experiments supporting next-generation LVV and AAV productionIdentify, onboard, and develop novel upstream technologies in collaboration with internal and external partnersOptimize production processes and support clinical and commercial scale-up Ability to design, execute, and lead a platform development strategy, including coordinating the work of junior colleagues and peersCraft and articulate timelines and resource projectionsLeverage knowledge of business needs to communicate progress, risks, and opportunities to senior leaders in the organizationSupport cross-functional development efforts e.g. downstream process development, analytical development, pilot plant production, high-throughput process development, etc.Support research-to-development transitions, including early-stage/pipeline molecular assessment activitiesSupport late-stage process development activities including process characterization Actively participate and support lab maintenance, buildout, and continuous improvement initiativesWork independently and within teams to design, execute, and analyze experimentsFlex between platform development and program development work as necessarySummarize and present data in group meetings and contribute to group discussions and team strategyRepresent GDPAD within cross-functional teamsSupport tech transfer and on-going activities with external collaborators and service providers (CDMOs, CROs)Model sophisticated knowledge management through authoring of detailed technical reports, study memos, and internal and external presentations/publications Maintain accurate and detailed laboratory notebook Basic Qualifications Degree in biological or chemical engineering, biochemistry, or bio-related field. PhD with 1+ year relevant industry experience; MS with 5+ years of relevant industry experience; BS with 7+ years relevant industry experience. Title/compensation will ultimately be commensurate with education, experience, and skillsetSubject matter expert with suspension culture of mammalian cells in shake flasks and stirred tank bioreactorsSubject matter expert in process developmentExpertise in viral vector process developmentWorking knowledge of scale up parameters for stirred tank bioreactorsProven ability to design experiments with DoE approaches, execute DoE designs and interpret the resultsIndependently motivated with ability to work in cross-functional teamsExperience interfacing with contract manufacturing and development organizationsAbility to communicate clearly and concisely through oral presentations and technical writingAbility to leverage literature, internal and external resources to solve problemsDesire to identify and advance the cutting edgePossess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environmentExperience giving presentations at industry conferencesExperience establishing industry (e.g. vendor) and/or academic collaborations Preferred Qualifications Experience with upstream processes intensification e.g. fed batch and perfusion development, process-analytical technology (PAT)Experience with cell line developmentExperience with media and feed development and optimizationExperience with process modeling, mechanistic modeling, and statistical interpretation of resultsKnowledge of metabolic flux and metabolic control analysisExperience with data pipelines and knowledge managementExperience with late-stage developmentTrack record of intellectual property generationundefined Additional Job Requirements Position Handles Hazardous Materials Position may require occasional travel (e.g. up to 10%) We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway. Compensation Overview Seattle - WA: $124,190 - $150,483 The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance. Benefits Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays. Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day. U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits How We Work Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working. Supporting People With Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Candidate Rights BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ Data Protection We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If this posting is missing required information required by local law or incorrect, contact BMS at TAEnablement@bms.comwith the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account. R1607258 : Senior Scientist, Gene Delivery and Editing Process Development