Senior Scientist, Gene Delivery and Editing Process Development , Cell Therapy Development
About the role
then...
. - Responsibilities: list of duties/responsibilities bullet points. UseResponsibilities
then- ... each duty.
- Qualifications: maybe combine Requirements, Qualifications, Skills. The posting has "Qualifications" section with Specific Knowledge, Skills, Abilities Required, Preferred/Development Supported, General Technical And Professional, Education/Experience/Licenses/Certifications. We can put under
Qualifications
with- items.
- Benefits: we have Benefits section. Use
Benefits
then- items.
- Pay: we have Compensation Overview with salary range. Use
Pay
then... maybe include range. - Schedule: not present; we should not create Schedule section if not stated. We must not repeat job title as heading. Do not put Job ID/requisition numbers as headings. We can include minor metadata in a short
or drop it. The posting ends with "R1606367 : Senior Scientist, Gene Delivery and Editing Process Development , Cell Therapy Development". That's job ID and title; we should drop it or put in a short p maybe but better to drop. We must preserve ALL substantive information; do not invent or summarize away detail. So we need to include all duties, qualifications, benefits, pay details. We must not include boilerplate like "We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway." That's maybe part of Qualifications? It's a statement encouraging apply; could be considered boilerplate? It's not legal but it's a generic encouragement. Might be okay to keep? The instruction says remove duplicated lines, cookie/navigation/legal/EEO/equal-opportunity/scam-warning boilerplate, duplicated lines, and application instructions. That encouragement is not exactly boilerplate but could be considered fluff. Safer to keep? It's substantive? It's not essential info about role. Might be considered filler. I'd drop it. Also need to remove "General General lab work including lifting up to 25 pounds." That's under Qualifications? Actually appears after "General Technical And Professional". It's a physical requirement; we should keep as part of Qualifications. We need to ensure we don't miss any duty bullet. Let's extract duties/responsibilities from the posting: The block after "Duties/Responsibilities" (note there is a line break missing period) includes: - Design and execute formulation and drug product development studies for viral vector (LVV, AAV) and nucleic acid/LNP (mRNA) products across liquid, frozen, and lyophilized presentations. - Lead freeze/thaw and cryopreservation studies and lyophilization cycle development; characterize freeze-concentration, ice nucleation, glass-transition (Tg′) and collapse behavior, and their impact on titer, potency, particle size/PDI, and aggregation. - Apply biophysical and colloidal characterization to elucidate degradation and instability mechanisms and to guide formulation decisions (e.g., DSC/mDSC, freeze-drying microscopy, DLS). - Develop and justify excipient, buffer, cryoprotectant, and surfactant systems from first principles rather than by platform default. - Design and interpret development lab stability studies to support phase-appropriate shelf-life and storage claims. - Maintain accurate experimental documentation using an electronic laboratory notebook; summarize and present scientific data and communicate progress to project teams. - Support technology transfer, process scale-up, and sterile drug product and fill/finish activities, partnering with internal subject-matter experts to build and apply GMP process knowledge. - Develop and maintain relationships with external collaborators and service providers (CMOs, CROs) required to produce advanced-modality materials. - Author technical reports and contribute to regulatory documentation, staying abreast of evolving global regulations and industry practices for cell and gene therapy products. - Maintain a safe work environment in accordance with policies, procedures, and regulations. We need to keep each as
- . Now Qualifications: The posting has: "Qualifications This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by management. Specific Knowledge, Skills, Abilities Required – core biophysical and stability expertise: Demonstrated expertise in the biophysical and colloidal stability of biologic or advanced-modality products, including the mechanisms of aggregation, phase behavior, surface adsorption, and excipient-driven stabilization.Hands-on experience with freeze/thaw and frozen-state stability, including the ability to distinguish and address bulk drug-product freeze/thaw versus cell/vector cryopreservation.Working proficiency with core biophysical techniques such as DSC/mDSC and/or freeze-drying microscopy (Tg′, collapse temperature) and dynamic light scattering (DLS), with sound judgment on which technique answers which stability question.Ability to design and justify buffer, cryoprotectant, and surfactant systems from scientific first principles. Preferred/Development Supported Hands-on lyophilization cycle development (collapse temperature, primary/secondary drying, cake structure, residual moisture, reconstitution), as opposed to general familiarity with lyophilization.Thermostabilization or cold-chain-reduction experience (e.g., moving a product toward lyophilized, refrigerated, or ambient-stable storage).Particle and subvisible characterization (e.g., NTA, MFI, particle size/PDI, encapsulation efficiency); further depth can be developed in-role.Exposure to sterile drug product operations and fill/finish (filtration, aseptic processing, container/closure), or clear readiness to develop this expertise with training and subject-matter-expert support. General Technical And Professional Familiar with statistical approaches for study design (e.g., DOE, ANOVA, TOST) and able to communicate data analysis conclusions rigorously to internal and external audiences.Experience with regulatory documentation, submissions, and cGMP/ICH guidelines.Ability to communicate clearly and concisely through oral presentation and technical writing, including development reports and regulatory filings. General General lab work including lifting up to 25 pounds. Education/Experience/Licenses/Certifications Ph.D. in Pharmaceutical Sciences, Chemistry, Biochemistry, Chemical/Biomedical Engineering, or equivalent; or M.S./B.S. in a related discipline.Ph.D. with 3+ years, M.S. with 6+ years, or B.S. with 10+ years of relevant formulation / drug product development experience. We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway." We need to extract substantive items, ignoring filler like "This job description does not state..." and "We hire for skills..." etc. We'll create bullet list under Qualifications: - Demonstrated expertise in the biophysical and colloidal stability of biologic or advanced-modality products, including mechanisms of aggregation, phase behavior, surface adsorption, and excipient-driven stabilization. - Hands-on experience with freeze/thaw and frozen-state stability, including ability to distinguish and address bulk drug-product freeze/thaw versus cell/vector cryopreservation. - Working proficiency with core biophysical techniques such as DSC/mDSC and/or freeze-drying microscopy (Tg′, collapse temperature) and dynamic light scattering (DLS), with sound judgment on which technique answers which stability question. - Ability to design and justify buffer, cryoprotectant, and surfactant systems from scientific first principles. - Preferred/Development Supported: Hands-on lyophilization cycle development (collapse temperature, primary/secondary drying, cake structure, residual moisture, reconstitution), as opposed to general familiarity with lyophilization. - Thermostabilization or cold-chain-reduction experience (e.g., moving a product toward lyophilized, refrigerated, or ambient-stable storage). - Particle and subvisible characterization (e.g., NTA, MFI, particle size/PDI, encapsulation efficiency); further depth can be developed in-role. - Exposure to sterile drug product operations and fill/finish (filtration, aseptic processing, container/closure), or clear readiness to develop this expertise with training and subject-matter-expert support. - Familiar with statistical approaches for study design (e.g., DOE, ANOVA, TOST) and able to communicate data analysis conclusions rigorously to internal and external audiences. - Experience with regulatory documentation, submissions, and cGMP/ICH guidelines. - Ability to communicate clearly and concisely through oral presentation and technical writing, including development reports and regulatory filings. - General lab work including lifting up to 25 pounds. - Education/Experience/Licenses/Certifications: Ph.D. in Pharmaceutical Sciences, Chemistry, Biochemistry, Chemical/Biomedical Engineering, or equivalent; or M.S./B.S. in a related discipline. - Ph.D. with 3+ years, M.S. with 6+ years, or B.S. with 10+ years of relevant formulation / drug product development experience. We could combine education bullets. Now Benefits: extract: "Benefits Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays. Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day. U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits" We need to keep substantive info; we can bullet: - Comprehensive benefit plans including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). - Flexible Time Off (FTO) for U.S.-based exempt employees:
- items.
- Pay: we have Compensation Overview with salary range. Use
- items.
- Benefits: we have Benefits section. Use