Senior Specialist, Quantitative Pharmacology and Pharmacometrics - Cardiometabolic and Ophthalmic Diseases
Our Quantitative Pharmacology and Pharmacometrics (QP2) Department in West Point, PA / Rahway, NJ is seeking a curious and collaborative Senior Scientist to support our rapidly expanding cardiometabolic and ophthalmology pipelines.
About the role
As a senior specialist, you will join cross-functional teams of experienced scientists to discover and develop novel therapeutic agents of various modalities for cardiometabolic and ophthalmic diseases. This role offers a unique opportunity to accelerate your professional career as a quantitative drug developer within one of the world’s most research-intensive biopharmaceutical companies, leveraging our end-to-end pipeline support.
Responsibilities
- Contribute to the development of model-based strategies (translational PK/PD strategies, mechanistic models, POPPK/PD, clinical trial simulations, etc.) for quantitative analyses across development programs and departments to inform and optimize drug discovery and all phases of drug development, including dose selection, clinical trial design, and go/no-go decisions.
- Represent QP2 on cardiometabolic and ophthalmology discovery, early clinical development, and late clinical development teams, using quantitative approaches to drive streamlined development within our growing portfolio.
- Collaborate with other functional areas, external vendors, and partners on study design, protocol development, study execution, reporting, and data interpretation.
Requirements
- A Ph.D. or equivalent degree OR a PharmD or equivalent degree with at least 2 years of experience OR an MS or equivalent degree with at least 4 years of experience. Experience must demonstrate increasing responsibility and independence in a similar role within pharmaceutical drug development, a regulatory agency, or academia.
- Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, chemical/biomedical engineering, or a related field.
- Experience performing population PK, PK/PD analyses using standard pharmacometrics software (e.g., NONMEM, Monolix, Phoenix, etc.).
- Strong written and verbal communication skills, interdisciplinary collaboration, and problem scoping and planning abilities.
Preferred Qualifications
- Knowledge of cardiometabolic and/or ophthalmology clinical drug development programs.
- Skills in experimental design, mathematical problem-solving, critical data analysis/interpretation, and statistics.
- Scientific understanding of biopharmaceutical and ADME properties of small molecules and/or biologics.
Skills
- Required: Clinical Study Design, Clinical Trial Designs, Clinical Trials, Data Modeling, Data Science, Data Visualization, Interdisciplinary Collaboration, Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics.
- Preferred: Database Design, Data Engineering, Machine Learning (ML), Waterfall Model.
Pay
The salary range for this role is $129,000.00 – $203,100.00. An employee’s position within the range will be based on factors including relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business needs. The successful candidate will also be eligible for annual bonus and long-term incentive, if applicable.
Benefits
We offer a comprehensive benefits package, including:
- Medical, dental, vision, and other insurance benefits for employees and their families.
- Retirement benefits, including a 401(k) plan.
- Paid holidays, vacation, compassionate leave, and sick days.
More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
Schedule
- Employee Status: Regular
- Relocation: VISA sponsorship available
- Travel Requirements: Flexible
- Work Arrangements: Hybrid