Associate Director, Quantitative Pharmacology and Pharmacometrics, Cardiometabolic

Our Quantitative Pharmacology and Pharmacometrics (QP2) Department within Research Laboratories in Rahway, NJ, and West Point, PA is seeking a curious, collaborative, and scientifically driven Associate Director to support our growing cardiometabolic pipelines. In this role, you will represent QP2 on cross-functional teams advancing novel therapeutic agents for cardiometabolic and ophthalmologic diseases, including small molecules, biologics, peptides, novel biological constructs, and other emerging modalities.

About the role

You will have the opportunity to grow your career as a quantitative drug developer while contributing to an end-to-end pipeline in a research-intensive biopharmaceutical company. We offer a collaborative, mission-driven environment where your scientific expertise can shape meaningful decisions and advance innovative therapies for patients.

Responsibilities

• Develop and apply model-based strategies, including translational PK/PD approaches, mechanistic models, population PK/PD analyses, and clinical trial simulations, to inform quantitative decision-making within and across development programs and departments.
• Optimize drug discovery and development decisions, including dose selection, clinical trial design, and go/no-go recommendations.
• Represent QP2 on cardiometabolic discovery, early clinical development, and late clinical development teams, using quantitative approaches to support evidence-based advancement of programs.
• Partner collaboratively with functional area colleagues, external vendors, and strategic partners to build aligned, quantitative, and model-informed approaches supporting drug discovery, development, and regulatory decision-making.
• Collaborate across disciplines on study design, protocol development, study execution, data interpretation, reporting, and communication of results.
• Maintain a strong understanding of global regulatory expectations and contribute to the development, presentation, and defense of regulatory documents and submissions.
• Work closely with pharmacometrics colleagues to provide scientific input on modeling strategies, analyses, interpretation, and reporting.

Requirements

• Ph.D. or equivalent degree with at least 4 years of relevant experience; PharmD or equivalent degree with at least 6 years of relevant experience; or MS or equivalent degree with at least 8 years of relevant experience.
• Relevant experience reflecting increasing responsibility and independence in pharmaceutical drug development, a regulatory agency, or academia.
• Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, chemical or biomedical engineering, or a related quantitative discipline.
• Experience conducting population PK and PK/PD analyses using standard pharmacometrics software, such as R, Matlab, Phoenix, NONMEM, Monolix, or similar tools.
• Strong written and verbal communication skills, with demonstrated ability to collaborate across disciplines, scope complex problems, and plan work effectively.
• Knowledge in modeling complex therapeutics and mechanistic modeling/QSP.

Preferred Qualifications

• Knowledge of cardiometabolic clinical drug development programs.
• Advanced skills in mathematical problem-solving, critical data analysis and interpretation, experimental design, and statistics.
• Scientific understanding of the biopharmaceutical and ADME properties of small molecules and/or biologics.
• A strong record of increasing responsibility, independence, and demonstrated impact in advancing drug development decisions through model-based approaches.

Skills

• Required: Business Intelligence (BI), Data Modeling, Data Science, Data Visualization, Stakeholder Relationship Management.
• Preferred: Database Design, Data Engineering, Machine Learning (ML), Software Development, Waterfall Model.

Pay

The salary range for this role is $156,900.00 - $247,000.00. An employee’s position within the salary range will be based on factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

Benefits

• Comprehensive medical, dental, vision, and other insurance benefits for employee and family.
• Retirement benefits, including 401(k).
• Paid holidays, vacation, compassionate, and sick days.
• Annual bonus and long-term incentive (if applicable).

Schedule

• Employee Status: Regular
• Relocation: Domestic
• Travel Requirements: 10%
• Flexible Work Arrangements: Hybrid
• Shift: 1st - Day