Associate Director, Quantitative Pharmacology

About the Role

We are seeking a highly motivated Associate Director (AD) to join the Quantitative Pharmacology (QP) group. This role combines scientific depth with cross-functional leadership to inform dose selection, trial design, and regulatory strategy from early development through submission for modalities including antibodies, siRNA, and gene therapies.

Responsibilities

• Drive model-informed drug development (MIDD) and pharmacometrics strategies in partnership with Clinical Pharmacology, Biostatistics, Clinical, and Translational teams to support regulatory and clinical decision-making.
• Lead the QP evaluation of one or more assets, accountable for timely delivery of population PK/PD, exposure-response, and translational modeling analyses.
• Represent QP at program and governance meetings, communicating quantitative insights clearly to non-modeling audiences.
• Contribute to regulatory interactions and author key components of regulatory documents related to QP (e.g., IB, briefing books).
• Mentor and develop junior scientists and foster a culture of scientific rigor and collaboration.
• Identify and implement process improvements, new modeling approaches, and innovative quantitative tools to enhance efficiency and impact.
• Ensure analyses and documentation are of the highest scientific quality and regulatory compliance.

Requirements

• PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field; or MS with 9+ years of relevant experience.
• 6+ years of post-doctoral or industry experience.
• Demonstrated expertise in population PK/PD, exposure-response, or mechanistic modeling (systems biology or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology, and R.
• Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).
• Hands-on experience with a broad range of quantitative and computational tools and a strong publication record.
• Exceptional communication and interpersonal skills, with the ability to influence and partner effectively across technical and non-technical teams.

Location

Tarrytown, NY | Cambridge, MA | Warren, NJ | Remote, USA

Schedule

4 days onsite

Pay

Salary Range (annually): $176,100.00 - $287,300.00

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• Annual bonuses or other incentive plans
• Equity awards
• Pension or retirement benefits, 401(k) company match
• Health and wellness programs, fitness centers
• Insurance benefits (e.g., medical, dental, vision, life, and disability)
• Paid time off
• Family support benefits

For additional information about Regeneron benefits in the U.S., visit Regeneron Total Rewards. For other locations, additional information will be provided during the recruitment process.