Jobs · Information Technology · California

Senior Security & Infrastructure Engineer

Zentalis Pharmaceuticals · San Diego, CA · 3 days ago
HybridInformation TechnologyFull-time

ESSENTIAL DUTIES AND RESPONSIBILITIES

  • Monitor, investigate, triage, and coordinate remediation for security alerts, identity events, vulnerabilities, and verified incidents across cloud, endpoint, server, and network environments.
  • Partner with MDR, managed SOC, and SOCaaS providers to review escalations, validate recommendations, improve detection logic, and ensure response workflows are effective.
  • Administer and improve Microsoft Entra ID, Conditional Access, MFA, identity governance, privileged access monitoring, access reviews, PKI, and certificate lifecycle management.
  • Support vulnerability management, patch compliance, security control administration, and risk prioritization from identification through remediation validation.
  • Coordinate remediation efforts to ensure corrective actions are communicated, completed, documented, and aligned to risk priorities.
  • Drive continuous improvement of security monitoring, alert response, operational procedures, and risk reduction efforts based on threat trends, lessons learned, and security assessments.
  • Assist with security assessments, audits, compliance reviews, and evidence collection.

Security Technology Ownership

  • Serve as a primary administrator for core security technologies, including: Microsoft Defender Suite, Microsoft Entra ID, Conditional Access, Endpoint Protection, Email Security, Vulnerability Management, Security Monitoring and Logging Solutions, SIEM, MDR, and SOCaaS Services.

Infrastructure, Cloud & Network Operations

  • Administer and support Microsoft 365, Azure, AWS, VMware, Azure Arc, hybrid infrastructure, and enterprise infrastructure platforms.
  • Troubleshoot complex infrastructure and platform issues while maintaining reliability, availability, performance, and secure configuration across enterprise systems.
  • Support infrastructure modernization, architecture, hardening, technology evaluations, implementation projects, and operational readiness activities.
  • Monitor and respond to infrastructure, application, and security alerts through LogicMonitor and other monitoring platforms; identify recurring issues and improve alerting or runbooks where needed.
  • Administer cloud backup, disaster recovery, data protection, recovery readiness, and immutable backup technologies.
  • Support commercial business needs by partnering with stakeholders, vendors, and technical teams on secure, reliable infrastructure solutions.
  • Participate in after-hours support and escalation activities as required.

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