Senior Scientist, Organoid

About the role

The position involves leading the development and optimization of differentiation and tissue engineering protocols to improve organoid fidelity, maturation, reproducibility, and relevance to the native tissue niche. Collaboration with cross-functional project teams is essential, as is the ability to drive project direction and prioritize based on company goals.

Responsibilities

• Independently design, develop, and optimize differentiation and tissue engineering protocols that improve organoid fidelity, maturation, reproducibility, and relevance to the native tissue niche
• Lead day-to-day execution while mentoring and developing scientists, setting expectations for rigor, documentation, and pace
• Synthesize experimental results, communicate progress clearly to scientific and program leadership, and help guide strategic decisions for platform and program development
• Collaborate closely with cross-functional project teams to share findings, integrate complementary approaches, and advance common objectives across related model system efforts
• Foster a team culture grounded in curiosity, urgency, flexibility, technical excellence, and transparency

Requirements

• PhD in Stem Cell Biology, Developmental Biology, or a related field, plus postdoctoral training or equivalent industry experience
• Experience with organoid microenvironment manipulation or bioengineering of tissue and/or organoid model systems
• Deep hands-on expertise in troubleshooting differentiation trajectories and complex model systems. Ideally expertise in setting up model systems; not just optimizing an already established protocol
• Exceptionally strong organizational and communication skills including thorough record keeping and priority-aligned executive summarization
• Strong analytical skills including experience interpreting sequencing datasets (SmartSeq2, single-cell RNA-seq, ATAC-seq, EM-seq, or similar)
• Strong work ethic and team-first mindset. Willing to do hands-on work, including routine and repetitive tasks, and step in when needed
• Able to thrive in a high-intensity, fast-paced, flexible startup environment
• Familiarity with reproductive biology, particularly ovarian development and the germ cell lifecycle, is a plus

Qualifications

The ideal candidate will bring hands-on experience developing new differentiation protocols, strong tissue engineering expertise, and a deep understanding of how cellular microenvironments influence tissue identity, maturation, and function.