Senior Scientist I/II, Bioprocess Development

About the role

We are seeking a Senior Scientist I/II, bioprocess development and microbial production subject matter expert and in-lab technical lead for a high impact, novel biological platform. This role will focus primarily on fermentation process development, translating early-stage biological systems into scalable and manufacturable processes.

Responsibilities

• Design, execute, and iterate on bioprocess experiments to support scalable fermentation process development including collaboration with Strain Development on strain improvements to support bioprocess productivity and robustness, media development, feeding design, mass transfer optimization, and process control
• Contribute to implementation and buildout of experimental frameworks for systematic process improvement, including DOE-based optimization and fermentation analytics
• Execute technology transfer to external CROs, CMOs, or manufacturing partners as subject matter expert as needed

Qualifications

• PhD in biochemical engineering, microbiology, chemical engineering, or a related discipline
• Scientist I: At least 5-7 years of professional experience, including 1+ years hands-on developing microbial fermentation processes in an industrial or translational setting
• Scientist II: At least 8-11 years of professional experience, including 3+ years hands-on developing microbial fermentation processes in an industrial or translational setting
• Demonstrated expertise in fermentation process development & scale-up, including optimizing parameters such as oxygen transfer, feeding regimes, media composition, etc.
• Experience optimizing high-cell-density microbial fermentations
• Hands-on experience developing and optimizing microbial fermentation across scales (e.g., 250 mL bench reactors through 50 L pilot-scale systems)
• Experience designing and executing fermentation experiments using systematic optimization approaches, such as DOE or structured process screening