Senior Scientist, Bioproduction and Bioprocessing

About the role

The Senior Scientist, Bioproduction & Bioprocessing leads the development, optimization, and execution of mammalian cell-based protein production workflows to support organizational research, development, and manufacturing needs. This role provides subject-matter expertise in cell line development, transient expression, and upstream bioprocessing, and ensures high-quality delivery of materials through collaboration with cross-functional teams. The Senior Scientist contributes to scientific innovation, process improvement, and customer support activities.

Responsibilities

• Lead and execute workflows for stable pool and stable cell line generation, including transfection, clone screening, productivity assessment, and documentation.
• Perform stable pool and transient experiments using CHOZN, CHOK1-sv, CHOK, HEK293, and other protein production-relevant cell lines.
• Develop, optimize, and scale transient protein expression processes for antibodies and recombinant proteins.
• Conduct upstream protein expression studies, including small-scale evaluations and preparation for scale-up.
• Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations.
• Analyze experimental data, prepare technical summaries, and present results to internal and external stakeholders.
• Collaborate with downstream purification, analytical development, and project management teams to ensure alignment and timely delivery of materials.
• Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists.
• Identify opportunities to enhance bioproduction workflows, including media/feed optimization, vector improvements, and process parameter refinement.
• Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability.
• Lead exploratory studies to assess emerging bioprocessing methods and integrate validated improvements into standard workflows.
• Contribute to internal innovation initiatives, including development of new production strategies, platform enhancements, and scientific capability expansion.
• Provide technical insight to support long-term bioproduction strategy and organizational growth.
• Maintain accurate, complete, and compliant laboratory records.
• Ensure adherence to organizational, regulatory, and safety standards.

Requirements

• PhD in biological sciences or related field with 10+ years of relevant industry experience (or Master’s degree with 13+ years of experience) in bioproduction, bioprocessing, or cell line development.
• Demonstrated expertise in stable cell line development and clone selection.
• Extensive hands-on experience with transient expression of antibodies or recombinant proteins.
• Strong foundation in mammalian cell culture and upstream protein expression.
• Experience with high-throughput screening, automation, or advanced analytical tools.
• Background in cell engineering, vector design, media/feed optimization, or bioprocess development.
• Prior experience in structured, milestone-driven industry or core laboratory environments.
• Good communication skills and ability to work collaboratively with internal team members and customers.
• Ability to travel up to 20%.

Benefits

• Comprehensive health, dental, vision, life, and disability insurance.
• Generous time off.

Pay

Base salary, annual bonus, and equity.