Senior Scientist

About the role

The W.M. Keck Biomedical Mass Spectrometry Lab – a part of the Biomolecular Analysis Facility Core at the University of Virginia – seeks a Senior Scientist to expand our work in the areas of proteomics and metabolomics using state-of-the-art instruments to support research within the institution in areas such as basic science research, the Cancer Center, and clinical projects.

Responsibilities

• Support the director through sample preparation, operation/maintenance of advanced mass spectrometers (Orbitrap ID-X – Vanquish Neo and Orbitrap Astral Zoom – Evosep Eno).
• Data analysis using advanced software packages (Proteome Discoverer, Compound Discoverer, Scaffold, etc).
• Advance institutional goals in proteomic and metabolomic profiling and translational research.
• Customer support of researchers within the institution.
• Use of existing techniques to answer current biological challenges and the development of new technologies in proteomics and metabolomics.

Requirements

• Doctoral degree, preferably a Ph.D. in Mass Spectrometry or in a very closely related field.
• Prior experience in qualitative and quantitative proteomics and metabolomics technology and nano-liquid chromatography and mass spectrometry (LC-MS; on Orbitrap Fusion, Orbitrap Astral, and/or Orbitrap ID-X).
• Familiarity with the entire metabolomics and/or proteomics pipeline (including sample preparation, LC and MS operation, and data analysis).
• Manage multiple projects between multiple laboratories.
• Demonstrate scientific productivity and have excellent oral and written communication skills.
• Demonstrate attention to detail and ability to learn new technologies, flexibility and time management skills.
• 5+ years’ direct experience in mass spectrometry or a MS in very closely related field and 10+ years’ experience in proteomics or metabolomics.
• Ability to collaborate across multiple disciplines and engage investigators in project design, execution and data analysis.
• Experience in publication and grant writing.
• Experience with Proteome/Compound Discoverer, Scaffold, MS Dial, MetaboAnalyst, etc.
• Advanced knowledge of Thermo mass spectrometers – operation and maintenance.

Qualifications

• Doctoral degree, preferably a Ph.D. in Mass Spectrometry or in a very closely related field.
• Prior experience in qualitative and quantitative proteomics and metabolomics technology and nano-liquid chromatography and mass spectrometry (LC-MS; on Orbitrap Fusion, Orbitrap Astral, and/or Orbitrap ID-X).
• Familiarity with the entire metabolomics and/or proteomics pipeline (including sample preparation, LC and MS operation, and data analysis).
• Manage multiple projects between multiple laboratories.
• Demonstrate scientific productivity and have excellent oral and written communication skills.
• Demonstrate attention to detail and ability to learn new technologies, flexibility and time management skills.
• 5+ years’ direct experience in mass spectrometry or a MS in very closely related field and 10+ years’ experience in proteomics or metabolomics.
• Ability to collaborate across multiple disciplines and engage investigators in project design, execution and data analysis.
• Experience in publication and grant writing.
• Experience with Proteome/Compound Discoverer, Scaffold, MS Dial, MetaboAnalyst, etc.
• Advanced knowledge of Thermo mass spectrometers – operation and maintenance.

Skills

• Excellent communication and team support.
• Highly motivated and able to work independently when designing and executing experiments.

Benefits

Salary will be commensurate with education and experience. This is an exempt-level, benefited position.

Pay

Salary will be commensurate with education and experience.

Schedule

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings.

Physical Demands

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings.

Additional Requirements

• Background checks and pre-employment health screenings will be conducted on all new hires prior to employment.

Contact

Contact For questions about the application process, please contact Jeremy Brofft, Senior Academic Recruiter at xmf9ad@virginia.edu. The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities.