Senior Scientist

About the role

ImmunEdge is a biopharmaceutical company dedicated to developing novel therapeutics for patients with serious or life-threatening diseases. Our team of experts in immunology and drug development is pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response.

Key Responsibilities

• Design, execute, and interpret in vivo efficacy, PK/PD, and mechanistic studies in relevant oncology and immunology models
• Develop and optimize ex-vivo assays, including MSD, ELISA, RNAseq, and functional readouts to support target biology and mechanism of action
• Perform and analyze multi-parameter flow cytometry experiments, including panel design, staining optimization, acquisition, and advanced data analysis to characterize immune and tumor cell populations
• Collaborate with discovery, translational, and biomarker teams to integrate in vivo and ex vivo data and guide program strategy
• Analyze complex datasets and communicate findings clearly to cross-functional stakeholders with diverse scientific backgrounds
• Contribute to study planning, experimental timelines, and data-driven decision making for program advancement
• Maintain accurate, well-organized experimental records while ensuring a safe, compliant, and reproducible lab environment
• Identify opportunities to improve in vivo and ex vivo assay platforms and evaluate emerging technologies relevant to ImmunEdge’s pipeline

Qualifications

• Ph.D. in Immunology, Pharmacology, Oncology, Molecular and Cellular Biology, or a related field; or M.S. with additional relevant industry experience
• 5+ years of industry experience in drug discovery or development, with significant hands-on experience in in vivo models
• Strong technical expertise in:
• In vivo pharmacology and disease models (oncology and/or immunology preferred)
• Flow cytometry (panel design, immune phenotyping, functional assays, data analysis)
• MSD, ELISA, and ex-vivo-based functional assays
• Experience integrating in vivo and ex-vivo data to support mechanism of action and translational hypotheses
• Proficiency with standard laboratory techniques such as ELISA, qPCR, western blotting, and cytokine assays
• Ability to independently plan and execute experiments, troubleshoot complex problems, and rigorously interpret scientific data
• Strong collaboration, communication, technical writing, and organizational skills
• Ability to thrive in a fast-paced, supportive start-up environment

Preferred Qualifications (Plus)

• Experience with PK/PD or bioanalytical assays
• Experience writing technical reports for IND-enabling studies
• Familiarity with immuno-oncology targets or immune-modulating therapeutics
• Prior CRO management or cross-functional project experience

Expected Salary Range

$154,000 - $170,000

Benefits

• Annual bonus plan
• Equity
• Comprehensive health (medical, dental, and vision) insurance
• 401k plan
• FSA plans (medical, dependent)
• Employee Assistance Plan
• Holiday and paid time off plan

Equal Opportunity Employer

We encourage candidates of all levels to apply as there is sometimes flexibility on job level and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity, and location.