Senior Research Scientist, Georgia Cancer Center
Job Summary
Responsibilities
- Research - 50%
- Independently plan, execute, analyze, and report on experiments to support the preclinical development of novel T cell therapy products.
- Genome editing and culturing human pluripotent stem cells in various conditions.
- Perform in vitro cell-based functional assays (cytotoxicity, cytokine, proliferation, etc.) for CAR T cell therapeutic candidate selection.
- Design, execute, and analyze flow cytometry experiments for CAR T cell product characterization.
- Reporting Research - 50%
- Support engineered T cell production activities (e.g., gene editing, T cell culture, cryopreservation, cell thawing).
- Culture both engineered primary T cell and suspension/adherent cell lines.
- Support IND-enabling preclinical studies.
- Cook up tasks across multiple projects and teams, demonstrating prioritization and planning.
- PhD or equivalent in Cell or Molecular Biology/Biological Sciences with 10 or more years research experience.
- Extensive hands-on experience with Molecular Biology (as PCR, qRT-PCR, ddPCR, DNA/RNA and protein preparation), Cloning, mammalian cell culture and transfection.
- Experience with multi-color flow cytometry, panel design, and data analysis.
- Willingness to accept responsibilities outside of initial job description
- Experience with human CAR T cell engineering.
- Experience using viral (lentiviral, retroviral or AAV) and/or non-viral gene delivery methods (e.g., CRISPR mediated knock-in or targeted genome integration).
- Experience with immunological assays, such as cytokine/chemokine analysis (e.g., ELISA or Luminex), cytotoxicity and in vitro cell based assays live cell analysis.
- Proficiency in using data analysis tools such as FlowJo and GraphPad Prism.
- Understanding of US FDA cGMP and international regulatory requirements is welcomed.
Required Qualifications
Preferred Qualifications
Shift/Salary/Benefits
This position is fiscal year based and works year-round. The intended work commitment or full-time equivalent (FTE) for this position is 1.0 and considered full-time. Salary and compensation is commensurate with education, experience, and achievements. The salary is subject to availability of funds.
Comprehensive benefits include medical, dental, vision, 13 paid holidays, vacation leave, sick leave, generous retirement plans, tuition waiver, wellness options, and much more!
Also, our full-time employees who have been employed with us successfully for more than 6 months can be considered for the Tuition Assistance Program.
Rank and salary are determined at the time of hire and are based on a variety of factors including but not limited to experience, education, credentials, specialty, training, etc. while also considering internal equity and market data.
Advancement through the faculty ranks at Augusta University is only through the annual Promotion and Tenure process in which faculty may apply if eligible (typically five-year increments). For more information on ranks, please review the Augusta University Promotion and Tenure Website:
https://www.augusta.edu/faculty-affairs/promotionandtenure.php
College/Department Information
The Medical College of Georgia is one of the nation’s largest medical schools by class size, with 260 students per class. The educational experience is anchored by the main campus in Augusta, regional clinical campuses for third- and fourth-year students across the state and a second four-year campus in Athens in partnership with the University of Georgia. MCG’s expanding partnerships with physicians and hospitals across Georgia currently provides about 350 sites where students can experience the full spectrum of medicine, from complex care hospitals to small-town solo practices. MCG and its teaching hospitals also provide postgraduate education to more than 500 residents and fellows in 50 different Accreditation Council for Graduate Medical Education-approved programs. Our researchers and clinicians focus on what most impacts the health of Georgia's and America’s children and adults, including cardiovascular biology and disease, cancer, neurosciences and behavioral sciences, public and preventive health, regenerative and reparative medicine, personalized medicine and genomics. Our physician faculty also share their expertise with physicians and patients at about 100 clinics and hospitals statewide.
About Us
Augusta University is Georgia's innovation center for education and health care, training the next generation of innovators, leaders, and healthcare providers in classrooms and clinics on four campuses in Augusta and locations across the state. More than 10,500 students choose Augusta for educational opportunities at the center of Georgia's cybersecurity hub and experiential learning that blends arts and application, humanities, and the health sciences. Augusta is home to Georgia's only public academic health center, where groundbreaking research is creating a healthier, more prosperous Georgia, and world-class clinicians are bringing the medicine of tomorrow to patient care today. Our mission and values make Augusta University an institution like no other.
Equal Employment Opportunity
Augusta University is proud to be an equal opportunity employer welcoming applicants from underrepresented groups, including individuals with disabilities and veterans.