Senior Research Scientist, Evidence Synthesis

About the role

We are seeking a Senior Research Scientist with technical experience in systematic literature reviews and/or indirect treatment comparisons (e.g., NMA, MAIC, STC) for health technology assessment submissions. This is a 100% remote opportunity available from Canada or the US. Our culture combines the agility of a start-up with the resources of a well-funded global organization.

Recent publications exemplifying our work include:

• Cope S, Chan K, Jansen JP. Multivariate network meta‐analysis of survival function parameters. Research Synthesis Methods. 2020;11(3):443-456. https://doi.org/10.1002/jrsm.1405
• Freemantle N, Xu Y, Wilson FR, et al. Network meta-analysis of immune-oncology monotherapy as first-line treatment for advanced non-small-cell lung cancer in patients with PD-L1 expression ≥50. Ther Adv Med Oncol. 2022;14:17588359221105024. https://doi.org/10.1177/17588359221105024
• Watts JM, Wang ES, Jonas BA, Wilson FR, et al. Matching-Adjusted Indirect Comparison of Olutasidenib and Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Relapsed/Refractory Acute Myeloid Leukemia. Adv Ther. 2026;43:1802–1815. https://doi.org/10.1007/s12325-026-03522-6
• Keeping ST, Cope S, Chan K, et al. Comparative effectiveness of nivolumab versus standard of care for third-line patients with small-cell lung cancer. J Comp Eff Res. 2020;9(18):1275–1284. https://doi.org/10.2217/cer-2020-0134

Responsibilities

• Subject Matter Expertise/Domain Knowledge:
  • Demonstrate understanding of the pharmaceutical industry, medical affairs, and health technology assessment requirements.
  • Oversee systematic literature reviews (clinical, economic, and/or health-related quality of life) and/or quantitative evidence synthesis studies.
  • Identify and communicate considerations relevant to evidence synthesis within deliverables (e.g., feasibility assessments, statistical analysis plans).
• Deliverable Creation:
  • Develop client-ready deliverables including protocols, statistical analysis plans, technical reports, and slides.
• Strategic Direction:
  • Contribute to short-term resourcing discussions.
• Project Management:
  • Manage project components by collaborating with team members to ensure high-quality outputs.
  • Ensure timely delivery and financial performance of projects or subcomponents.
  • Estimate required hours, identify challenges early, and propose solutions to the project lead.
• Client Management:
  • Review update slides, minutes, and actions for client studies.
  • Lead client calls and respond to emails, involving senior team members as needed.
• Line Management/Team Development:
  • Create development plans and mentor direct reports.
• Business Development:
  • Contribute to proposal and presentation development under guidance of senior team members.
  • Participate in new business meetings, including concept ideation.

Requirements

• Master’s degree in health services research (e.g., health economics, public policy, epidemiology, biostatistics, public health, or science such as biology/biochemistry).
• 4-6 years of professional experience.

Skills

• Willingness and desire to learn and share knowledge.
• Excellent oral and written communication skills.
• Proficiency with Microsoft Office and EndNote.
• Proficiency in R/R Shiny (advantageous).

Pay

Reasonable estimate of the current compensation range: $100,000 USD - $140,000 USD.

Benefits

• Discretionary annual bonus.
• Health insurance.
• Retirement savings benefits.
• Life insurance and disability benefits.
• Parental leave.
• Paid time off for sick leave and vacation.