Senior Research Associate
Onyx Bio · Berkeley, CA · 2 wk ago
On-siteResearch$100k–$130k/yrFull-time
Key Responsibilities
- Data generation
- Run single-cell genomics workflows end-to-end: PBMC thaw and prep, 10x Chromium chip loading, library construction, and QC.
- Prepare and ship samples for external multiomics assays (proteomics, metabolomics); manage vendor handoffs, turnaround, and data return.
- Execute protocols with high precision and consistency; own the quality and reproducibility of the data you generate.
- Contribute to SOP development, optimization, and troubleshooting to continually drive down assay variability.
- Kit platform and operations
- Assemble, QC, and ship biosample collection kits for mobile phlebotomy and clinical research sites.
- Collaborate with the Clinical Research team to coordinate shipping logistics for kits for member study visits.
- Manage inventory and procurement: reorder points, purchasing, receiving, vendor relationships, and qualifying new suppliers.
- Support day-to-day lab readiness: equipment upkeep, consumables, freezer and inventory maps, and BSL-2 safety/PPE compliance.
- Growth
- Take on greater assay-development responsibility, and help design and program automated liquid-handling workflows.
- BS or MS in molecular biology, biochemistry, immunology, bioengineering, or a related field, plus 3-5+ years of hands-on wet-lab experience.
- An obsession for precision at the bench—accurate, reproducible pipetting and a track record of clean, careful work.
- Hands-on experience with core molecular biology techniques (nucleic acid extraction, PCR, library prep, QC).
- Hands-on experience in cell-based workflows (washing, cell counting, etc.).
- Hands-on experience with single-cell platforms (10x Genomics Chromium; Parse, Scale Bio, or similar).
- Strong organization, reliable follow-through, and documentation discipline—you can own logistics and inventory without dropping balls.
- Comfortable wearing many hats and moving fluidly between several high priority tasks across bench science and hands-on operations.
- Able to work on-site in a BSL-2 lab handling human biospecimens.
- NGS library preparation and QC (TapeStation/Bioanalyzer, Qubit).
- Flow cytometry and cell sorting for single-cell preparation.
- Exposure to automated liquid handlers (Tecan, Hamilton), or strong interest in learning.
- Experience handling PBMCs and cryopreserved samples.
- Cold-chain shipping experience and/or IATA/DOT dangerous-goods certification (or willingness to obtain it).
- Familiarity with LIMS or sample-tracking systems.
- Basic data/computational literacy (Python or R) a plus.
- Competitive salary ($100k – $130k) and meaningful equity.
- New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time.
- Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
- Comprehensive health, dental, and vision insurance.
- Flexible PTO policy.
- Professional development opportunities.