Jobs · Research · California

Senior Research Associate

Onyx Bio · Berkeley, CA · 2 mo ago
On-siteResearch$100k–$130k/yrFull-time

Key Responsibilities

  • Data generation
    • Run single-cell genomics workflows end-to-end: PBMC thaw and prep, 10x Chromium chip loading, library construction, and QC.
    • Prepare and ship samples for external multiomics assays (proteomics, metabolomics); manage vendor handoffs, turnaround, and data return.
    • Execute protocols with high precision and consistency; own the quality and reproducibility of the data you generate.
    • Contribute to SOP development, optimization, and troubleshooting to continually drive down assay variability.
  • Kit platform and operations
    • Assemble, QC, and ship biosample collection kits for mobile phlebotomy and clinical research sites.
    • Collaborate with the Clinical Research team to coordinate shipping logistics for kits for member study visits.
    • Manage inventory and procurement: reorder points, purchasing, receiving, vendor relationships, and qualifying new suppliers.
    • Support day-to-day lab readiness: equipment upkeep, consumables, freezer and inventory maps, and BSL-2 safety/PPE compliance.
  • Growth
    • Take on greater assay-development responsibility, and help design and program automated liquid-handling workflows.

    Required Qualifications

    • BS or MS in molecular biology, biochemistry, immunology, bioengineering, or a related field, plus 3-5+ years of hands-on wet-lab experience.
    • An obsession for precision at the bench—accurate, reproducible pipetting and a track record of clean, careful work.
    • Hands-on experience with core molecular biology techniques (nucleic acid extraction, PCR, library prep, QC).
    • Hands-on experience in cell-based workflows (washing, cell counting, etc.).
    • Hands-on experience with single-cell platforms (10x Genomics Chromium; Parse, Scale Bio, or similar).
    • Strong organization, reliable follow-through, and documentation discipline—you can own logistics and inventory without dropping balls.
    • Comfortable wearing many hats and moving fluidly between several high priority tasks across bench science and hands-on operations.
    • Able to work on-site in a BSL-2 lab handling human biospecimens.

    Nice to Have Qualifications

    • NGS library preparation and QC (TapeStation/Bioanalyzer, Qubit).
    • Flow cytometry and cell sorting for single-cell preparation.
    • Exposure to automated liquid handlers (Tecan, Hamilton), or strong interest in learning.
    • Experience handling PBMCs and cryopreserved samples.
    • Cold-chain shipping experience and/or IATA/DOT dangerous-goods certification (or willingness to obtain it).
    • Familiarity with LIMS or sample-tracking systems.
    • Basic data/computational literacy (Python or R) a plus.
    • Benefits & Compensation

      • Competitive salary ($100k – $130k) and meaningful equity.
      • New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time.
      • Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
      • Comprehensive health, dental, and vision insurance.
      • Flexible PTO policy.
      • Professional development opportunities.

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