Senior Manager, US Medical Affairs

Role Summary

The Senior Manager, US Medical Affairs supports execution of Dyne’s US Medical Affairs strategy for the Duchenne Muscular Dystrophy (DMD) program. This role contributes to critical launch readiness activities and supports the planning and delivery of US Medical initiatives, including KOL engagement, congress execution, medical education efforts, and cross-functional coordination.

Primary Responsibilities

• Supports execution of US Medical Affairs tactical plans for the DMD program
• Aids in implementing scientific platform materials, congress planning, and medical education initiatives
• Contributes to cross-functional launch readiness activities to ensure alignment with program milestones
• Supports development and deployment of DMD-focused scientific materials, disease state education resources, and field medical tools
• PARTNER WITH THE US MSL TEAM TO SUPPORT KOL IDENTIFICATION, ENGAGEMENT PLANNING, INSIGHT GATHERING, AND FIELD METRIC TRACKING
• TRANSLATES FIELD INSIGHTS INTO ACTIONABLE RECOMMENDATIONS FOR MEDICAL AFFAIRS AND CROSS-FUNCTIONAL TEAMS
• TRACKS AND MONITORS FIELD ACTIVITY AND ENGAGEMENT EFFECTIVENESS
• CONTRIBUTES TO DEVELOPMENT OF SCIENTIFIC MATERIALS, FIELD TOOLS, AND EDUCATIONAL CONTENT
• PROVIDES MEDICAL REVIEW FOR PROMOTIONAL MATERIALS THROUGH THE PROMOTIONAL REVIEW COMMITTEE (PRC)
• Maintains deep and current scientific knowledge in DMD and Dyne’s therapeutic platform
• SUPPORTS PLANNING AND EXECUTION OF MEDICAL CONGRESSES, INCLUDING ONSITE ACTIVITIES ALIGNED TO DMD MILIEU
• COORDINATES LOGISTICS AND EXECUTION OF US ADVISORY BOARDS AND EXPERT ENGAGEMENTS
• PARTNER WITH PATIENT ADVOCACY, MARKET ACCESS, AND COMMERCIAL TEAMS TO SUPPORT ALIGNED MEDICAL ACTIVITIES
• ENSURES ALL ACTIVITIES COMPLY WITH US REGULATORY, LEGAL, AND COMPLIANCE STANDARDS
• MODEL DYNE’S CORE VALUES THROUGH COLLABORATION, ACCOUNTABILITY, AND SCIENTIFIC INTEGRITY

Education and Skills Requirements

• Advanced scientific or clinical degree required (PhD, PharmD, MD, or equivalent)
• 7+ years of relevant Medical Affairs experience in pharmaceutical or biotechnology industry
• Rare disease experience preferred; neuromuscular disease experience a plus
• Experience supporting US-based medical tactics, congress activities, or field medical programs
• Strong scientific acumen with ability to translate clinical data for diverse audiences
• Excellent written and verbal communication skills
• Ability to operate effectively in a fast-paced, evolving environment with competing priorities
• Demonstrated ability to build collaborative relationships with internal and external teams
• Positive team orientation with strong alignment to Dyne’s Core Values
• Passion for improving the lives of patients with neuromuscular diseases

Pay

MA Pay Range $165,000—$190,000 USD