Senior Manager, Clinical Site Payments, Portfolio Management

General Description

The Senior Manager, Clinical Site Payment Portfolio Management is responsible for global financial oversight, reconciliation, and portfolio-level governance of investigator grant payments across BeOne-sponsored clinical trials. This role partners closely with the Director of Clinical Site Payments, Head of CBO, Regional Clinical Site Payments teams, R&D Finance, Global R&D Sourcing (GRDS), payment vendors, and cross-functional stakeholders to ensure accurate financial reporting, accrual integrity, and compliance with SOX and internal control frameworks.

Portfolio Financial Oversight & Reconciliation

• Lead monthly reconciliation of global investigator grant expenses, ensuring alignment across site payments, vendor disbursements, and financial ledgers
• Review and validate payment vendor drawdowns, ensuring appropriate funding levels and supporting documentation
• Partner with Regional Clinical Site Payments teams and vendors to investigate discrepancies and drive timely resolution
• Maintain a consolidated portfolio view of payments, accruals, commitments, and outstanding liabilities

Purchase Order (PO) & Financial Lifecycle Management

• Oversee creation, maintenance, and lifecycle management of Purchase Requisitions (PRs) and Purchase Orders (POs) for clinical site payments and vendors
• Avoid inaccuracies in POs by ensuring they accurately reflect study budgets, amendments, and forecasted spend
• Monitor PO balances, utilization, and close-out activities to support financial accuracy and audit readiness
• Manage vendor invoice review, validation, and approvals in collaboration with GRDS and R&D Finance

Accruals, Close Process & BvA Analysis

• Own monthly PO accrual analysis and reporting in partnership with R&D Finance and GRDSEnsure accurate and timely investigator grant accruals in compliance with financial close timelines and SOX requirements
• Perform Budget vs. Actuals (BvA) analysis at study and portfolio level, identifying key variances, trends, and financial risks
• Partner with R&D Finance and Treasury to support financial close activities and ensure completeness of recorded expenses

Clinical Site Financial Closeout & Unbilled Liability Forecasting

• Develop deep understanding of site-level financial closeout processes to ensure completeness of final investigator grant expenses
• Partner with GRDS and R&D Finance to identify and project outstanding expenses incurred but not yet invoiced by sites
• Ensure accrual coverage for unbilled costs through closeout periods and study transitions
• Support accurate financial representation of liabilities across the clinical portfolio

Financial Modeling, Forecasting & Scenario Analysis

• Develop and maintain financial models to support: Accrual forecasting and cash flow projections
• Scenario analysis (e.g., enrollment changes, study delays, vendor mix, FX rate impacts)
• Internalization strategies for clinical payments
• Lead short-term and long-term forecasting for internalized countries in partnership with R&D Finance and Treasury
• Analyze impact of business and operational changes on financial performance and portfolio risk

Data Alignment, Reporting & Payment Analytics

• Own Clinical Site Payment KPIs, metrics framework, and reporting cadence
• Develop and maintain analytics dashboards (e.g., Power BI) to monitor: Payment cycle times, accrual vs. actual accuracy, Vendor performance and financial trends
• Partner with: CBO Budget Planning & Strategy, Clinical Site Contracts, Clinical Site Data Hub

Supervisory Responsibilities

None

Computer Skills

• Advanced knowledge Microsoft Office - Word, Excel, Power Point and MS Outlook
• Smartsheet, SharePoint, MS Teams

Other Qualifications

• Fluent in both written and verbal English
• Strong proficiency in Excel, financial systems (SAP, Oracle, Ariba, Agiloft) and vendor clinical payment platforms
• The ability to manipulate and interpret key financial data effectively
• Exceptional accuracy and attention to detail
• Proven ability to prioritize workload and manage multiple tight deadlines effectively in a fast-paced environment
• Strong interpersonal skills, with demonstrated leadership, negotiation, analytical, and problem-solving abilities
• Capable of multitasking and meeting compressed timelines
• Critical thinker with a proactive approach to problem-solving
• Self-starter with the flexibility to work independently while exercising sound judgment and initiative
• Prior experience in clinical trial finance, clinical site budgeting, vendor sourcing, clinical operations, clinical payments, finance, and/or accounting
• Proven ability to build and maintain financial models
• Cash flow forecasting and accrual projections
• Background in clinical and drug development within the biotech/pharmaceutical industry
• Experience in clinical business operations, business process management, and project management
• Strong understanding of SOX compliance and financial control frameworks
• Experience supporting financial close processes and audit readiness
• High attention to detail with strong focus on accuracy, documentation, and auditability

Travel

As Needed

Education

• Bachelor’s degree from an Accredited College, and at least 7+ years’ experience in finance, biotech, pharmaceuticals, or a related field in the biotech/pharmaceutical industry

Global Competencies

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Communicates with Clarity

Salary Range

$136,400.00 - $181,400.00 annually