Senior Manager, Clinical Site Payments Processes and Systems

The Senior Manager, Clinical Site Payments Processes and Systems role is based in the United States.

About the role

Lead the development, governance, and continuous improvement of global clinical site payment processes and systems. Drive operational excellence by ensuring payment workflows are scalable, compliant, audit-ready, and aligned across cross-functional teams. Oversee system configuration, reporting, training, and vendor governance while supporting efficient clinical trial execution across global markets.

Responsibilities

• Lead the design, documentation, governance, and continuous improvement of end-to-end clinical site payment processes to ensure efficiency, compliance, scalability, and audit readiness.
• Develop and manage training programs, onboarding materials, knowledge repositories, and standardized operating procedures for internal teams and key stakeholders.
• Configure and maintain clinical site payment platforms, ensuring accurate implementation of contracts, budgets, amendments, payment schedules, and site-level configurations.
• Establish governance standards, validation controls, reconciliation processes, and quality checks to maintain data integrity across payment systems and vendor platforms.
• Produce executive-ready dashboards, KPIs, metrics, and operational reports that support leadership decision-making, vendor oversight, and continuous process improvement.
• Collaborate with cross-functional teams including Clinical Operations, Finance, Treasury, Procurement, Compliance, Quality, Internal Audit, and external vendors to align payment processes and resolve operational issues.
• Maintain reconciliation activities related to contracts, budgets, payment execution, and study startup/closeout while maintaining documentation that supports regulatory and audit requirements.

Requirements

• Bachelor's degree or equivalent professional experience in clinical operations, finance, business, life sciences, or a related discipline.
• Significant experience managing clinical site payment operations, clinical trial financial processes, or related clinical operations within the pharmaceutical, biotechnology, or CRO industry.
• Strong knowledge of clinical trial payment workflows, contract amendments, budget management, reconciliation processes, and vendor oversight.
• Experience working with clinical payment platforms, CTMS, and enterprise systems such as SAP, Oracle, Ariba, Agiloft, or similar technologies.
• Advanced proficiency with Microsoft Excel, Power BI, SharePoint, Smartsheet, and other reporting and collaboration tools.
• Demonstrated ability to build process documentation, training materials, governance frameworks, dashboards, and executive-level reporting.
• Excellent analytical, organizational, communication, and stakeholder management skills with the ability to coordinate multiple cross-functional initiatives simultaneously.
• Proven ability to identify operational risks, improve business processes, and deliver scalable solutions within highly regulated environments.

Benefits

• Annual base salary ranging from $136,400 to $181,400, based on experience, qualifications, and location.
• Opportunity to participate in discretionary equity awards and the Employee Stock Purchase Plan (ESPP).
• Comprehensive medical, dental, and vision insurance.
• 401(k) retirement plan with additional savings options.
• Flexible Spending Accounts (FSA) and Health Savings Account (HSA) options.
• Life insurance coverage and wellness-focused benefits.
• Paid Time Off (PTO) and comprehensive employee wellness programs.
• Remote work opportunity within the United States.
• A collaborative environment focused on innovation, continuous improvement, and professional growth.