Senior Manager, Business Development

MacroGenics is a leader in the discovery and development of innovative medicines utilizing next-generation antibody-based technologies. Our team of 150+ dedicated individuals advances a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceutical and biotechnology companies globally.

About the role

The Sr. Manager, Business Development occupies a high-impact, cross-functional seat bridging early-stage discovery, early clinical development, and corporate partnerships. This individual will shape MacroGenics’ pipeline, with an emphasis on immuno-oncology and novel antibody-based biologics, serving as the operational glue for internal program execution and key asset alliances. The ideal candidate will identify strategic opportunities, drive internal product strategy across Research, Clinical Development, and Regulatory, and manage strategic relationships with external partners.

Responsibilities

• Business Development & Alliance Management
  • Lead teams in creating comprehensive development plans, including identifying alternatives and scenario planning in cooperation with other functional areas.
  • Partner with functional areas (e.g., research, clinical, finance) to refine and build integrated program strategy.
  • Conduct competitive landscape analyses to inform business development priorities and decision-making.
  • Attend business and scientific conferences to meet prospective partners and maintain understanding of current industry trends.
  • Develop business development communication materials and present corporate overview and programmatic details to prospective collaborators.
  • Identify out-licensing and strategic partnering opportunities; assess external product candidates and technology platforms for in-licensing.
  • Oversee existing or new partnership alliances and participate in related governance committees.
  • Maintain deep operational familiarity with partnership agreements, ensuring both organizations fulfill contractual obligations, steering committee mandates, and milestone triggers.
  • Serve as the primary point of contact for external partner counterparts; actively monitor partnership health, proactively identify areas of friction, and facilitate conflict resolution regarding operational direction.
• Product Planning
  • Maintain a current understanding of key therapies and research approaches pertinent to MacroGenics’ pipeline of oncology, autoimmune, and infectious disease products.
  • Monitor competitor clinical data disclosures (e.g., ASCO, ESMO, AACR, PubMed) and assess their strategic impact on our pipeline.
  • Compile intelligence from key scientific meetings and present recommendations for consideration.
  • Formulate Target Product Profiles (TPPs) for pipeline projects; identify and drive commercially meaningful, sustainably differentiated candidates early in their development cycle.
  • Conduct primary and secondary market research to confirm hypotheses around unmet medical needs.
  • Provide strategic guidance on novel oncology mechanisms of action, including T-cell engagers, antibody-drug conjugates (ADCs), combination regimens, and I-O assets, anticipating how shifting standards of care impact market adoption.
  • Present synthesized market research findings and provide meaningful recommendations to inform development of current and future pipeline programs.
  • Deliver presentations to senior management and influence diverse sets of stakeholders, including clinical, research, and finance.

Qualifications

• Education & Credentials
  • Bachelor’s degree required; B.S. in biology or related discipline.
  • Advanced degree (MS, MBA, PhD) highly preferred.
• Experience
  • Minimum 3 years of experience in a biotech, pharma, and/or healthcare consulting company with exposure to product planning, alliance management, and/or program management.
• Knowledge, Skills, and Abilities
  • Familiarity with antibody-based therapeutics.
  • Understanding of the drug discovery and development process.
  • Proven scientific acumen, communication skills, and an analytical mindset.
  • Must have a "roll-up their sleeves" work style and understand both tactical and strategic requirements.
  • Demonstrated ability to independently evaluate oncology clinical trial data.
  • Ability to manage multiple projects and work collaboratively across multi-disciplinary teams.
  • Knowledge of program management methodologies such as integrated timelines and stage-gate development processes in a biotech or pharma environment.
  • Excellent communication and interpersonal skills, including experience leading cross-functional teams and successfully interacting with executive-level management and/or external corporate partners.
  • Strong work ethic and self-starter.

Preferred Qualifications

• MBA or graduate degree in science.
• Experience in Oncology or Immunology.

Pay

The annual rate of pay for this position ranges from $156,600 to $238,800. This role is eligible for the Company’s discretionary bonus and discretionary equity incentives.

Benefits

• Medical, dental, vision, and prescription coverage.
• Employee wellness resources.
• 401(k) plan with employer match.
• Employee Stock Purchase Plan (ESPP).
• Paid time off and paid parental leave.
• Disability benefits.