Senior Lab Research Technician

About the role

The Senior Lab Research Technician provides senior-level technical assistance and performs routine laboratory activities for a translational medicine laboratory studying how body composition changes, including muscle and fat loss, impact cancer prevention and survival. This position will report directly to the Principal Investigator and provides oversight and management of scientific research problems designed to understand mechanisms of cancer-associated wasting during early disease for future development of anti-cancer and anti-weight loss therapies.

Responsibilities

• Assist with the establishment of a new research laboratory
• Maintain a mouse colony, including weaning, genotyping, breeding, and maintaining records
• Plan and execute animal and cell culture experiments
• Process murine and human blood and tissue samples
• Perform routine laboratory housekeeping activities
• Maintain two IACUC protocols and IBC compliance
• Perform laboratory assays focused on anatomic, functional, and biochemical characterization of muscle, adipose tissue, and tumor
• Compile and analyze data from assays
• Exercise judgment in prioritizing work to meet the objectives and deadlines associated with generating data for grant renewals, grant proposals, and submission or revision of manuscripts
• Provide high-level technical expertise in the design, performance, and troubleshooting of complex laboratory experiments
• Analyze, interpret, and manage experimental data
• Collaborate with the laboratory's Principal Investigator (PI) in developing projects for laboratory personnel and provide functional supervision and training of laboratory personnel
• Maintain compliance with regulatory agencies for the laboratory, including lab personnel safety, chemical safety, biosafety, IACUC, and IBC
• Serve as a resource for other laboratory members, including technicians, graduate students, undergraduates, and/or postdocs, in experimental design, evaluating research methodologies, and interpreting data
• Work independently with minimal supervision from the PI

Minimum Qualifications

• Bachelor's degree in a related field and five years related laboratory research experience required, or equivalent combination of education and experience
• Experience with in vivo animal research, molecular biology, and cell culture techniques
• Knowledge of physiology and metabolism
• Proficiency with the procedures required for successfully conducting the protocols carried out in lab
• Experience with quantitative RT-PCR, Western Blot, ELISAs, and database management
• Knowledge of statistics, as applied to biomedical research
• Experience working with mice (including administration of substances, euthanasia, and tissue harvest), managing genetically modified mouse colonies, and genotyping
• Proficiency with spreadsheets and database applications
• Effective writing and organizational skills

Desirable Qualifications

• Experience with Microsoft Office, Excel, PowerPoint, GraphPad Prism, UVM Click, and VOS
• Experience in cancer, energy balance, or nutrition-related research

Pay

$28.00 - $32.00/hour

Schedule

Occasional evening and/or weekends required (if non-exempt position, may result in overtime). This position is ineligible for telework due to the essential functions.

Other Information

A probationary period may be required. Contingent on continued funding. Background Check required for this position.