Research Lab Technician Senior

Responsibilities

• Perform injections, blood collection, perfusions, and tissue harvest with high precision and consistency across repeated procedures to minimize experimental variability
• Process heart tissue, spleen, bone marrow, and other organs using standardized cell isolation protocols
• Maintain detailed records of mice cohorts
• Monitor animal health with strong situational awareness, recognizing subtle changes in posture, breathing, or behavior, and escalating concerns promptly
• Prepare samples for downstream analyses including flow cytometry, histology, sequencing, and proteomics
• Follow and help maintain standardized laboratory protocols for perfusion, tissue digestion, blood collection, and related procedures
• Prepare reagents and organize surgical instruments in advance of harvest days to support efficient, error-free processing of large cohorts
• Communicate clearly and immediately about problems, uncertainty, or deviations from expected outcomes
• Maintain a well-organized inventory of laboratory materials and place order requests with the Internal Medicine Purchasing team
• Attend scheduled laboratory meetings and contribute to discussions of experimental design and troubleshooting
• Analyze data for publications under the direction of the PI
• Other duties as assigned

Required Qualifications

• A bachelor's degree in a biological or health science discipline, with an advanced degree or additional training preferred
• Previous experience in a bench science research laboratory is required
• Demonstrated ability to perform repeated procedures (such as injections, tissue harvest, or sample processing) with precision and consistency
• Experience with phenotyping animal models, RNA and protein extraction protocols, cell culture, and molecular biology techniques (e.g. quantitative PCR, next-generation sequencing)
• Ability to maintain detailed, accurate records of experiments and mouse cohorts across multiple concurrent studies
• Effective written and verbal communication skills, including the ability to report problems or uncertainty promptly
• Flexibility to conduct experiments over some weekends as needed
• Understands and demonstrates the core concepts of Patient and Family Centered Care, including Respect and Dignity, Information Sharing, Participation, and Team Collaboration

Desired Qualifications

• A background in immunology and/or vascular biology
• Experience with organ processing and cell isolation from murine models, particularly heart, spleen, vascular tissues, and bone marrow
• Demonstrated commitment to continuous skill development, including willingness to take on advanced responsibilities such as managing large cohorts, training new staff, or preparing samples for sophisticated analyses
• Familiarity and openness toward project management tools and communication platforms