Senior Facilities Engineering Manager

Join Immatics and shape the future of cancer immunotherapy, helping to make a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, with the broadest PRAME franchise spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients worldwide.

About the Role

We are seeking a Senior Facilities Engineering Manager to lead the Facilities Engineering team responsible for ensuring GMP manufacturing equipment, utilities, and facility assets are qualified, validated, reliable, and available for production and lab operations. This role bridges Facilities Engineering, CMC Manufacturing, CSV, and Quality (OQA, QAV), preparing for Phase III manufacturing and commercial launch while applying reliability engineering principles.

Location: 13203 Murphy Road Suite 100, Stafford, TX 77477
Reports to: Director, Facilities, Engineering, & Asset Lifecycle

Responsibilities

• Lead validation and qualification of GMP manufacturing equipment, process utilities, HVAC systems, cleanrooms, compressed gases, and more.
• Oversee IQ, OQ, PQ, requalification strategy, and validation lifecycle management.
• Develop and manage preventive maintenance, predictive maintenance, reliability-centered maintenance, asset criticality analysis, and equipment lifecycle planning to maximize uptime and improve overall equipment effectiveness.
• Support the transition from late-stage clinical manufacturing to commercial operations.
• Partner with Quality to manage deviations, lead equipment investigations, execute CAPAs, and support change control.
• Lead, mentor, and coach equipment validation engineers and reliability engineers.
• Manage engineering budgets and KPIs.
• Perform engineering duties as necessary.

Requirements

Basic Qualifications:

• Bachelor’s degree in Mechanical, Electrical, Chemical Engineering, or related field.
• 7+ years in pharmaceutical or biotech engineering within a GxP-regulated manufacturing or laboratory environment, with 5+ years directly leading teams.

Preferred Qualifications:

• Strong knowledge of FDA and cGMP requirements.
• Deep experience with IQ/OQ/PQ and exposure to CSV interfaces.
• Expertise in cleanrooms and critical utilities.
• Experience supporting commercial biologics or cell therapy manufacturing.
• Familiarity with CMMS, BMS/EMS, and digital maintenance systems.
• PMP or similar certification is advantageous.
• Demonstrated understanding of 21 CFR Part 11, 21 CFR Part 210, 21 CFR Part 211, EU Annex 1, and USP.
• Experience in writing and reviewing Deviations, CAPAs, investigations resulting from OOS/OOT, environmental excursions, lab investigations leading to Change Controls for QMS.

Schedule

Monday to Friday, 8:00 am – 5:00 pm; on-call support as needed.

Benefits

• Comprehensive health, dental, and vision insurance at competitive rates.
• 4 weeks of vacation, granted up front each year (prorated for first and last year).
• 12 company-paid holidays.
• 7 days of sick time.
• 100% employer-paid life insurance up to 1x annual salary (up to $100,000).
• 100% employer-paid short- and long-term disability coverage.
• 401(k) with immediate eligibility and company match:
  • 100% match up to 3% of base salary for the first two years.
  • 4% match for years 2-3.
  • Up to 5% match from the fourth year onward.
• Partially paid parental leave for eligible employees.
• Additional voluntary benefits, including accident, hospital indemnity, critical illness insurance, identity theft protection, and pet insurance.