Senior Director, Translational Sciences

Acadia Pharmaceuticals · South San Francisco, CA · 2 wk ago

HybridAnalystFull-time

Develop and lead translational biology strategies to interrogate disease biology and drug MoA, driving execution across candidate targets and therapeutic programs
Design and implement preclinical neurology and neurophysiology studies to address key MoA questions across the portfolio
Partner across research and development teams to develop and test hypotheses supporting target validation and candidate progression
Define MoA strategies for preclinical evaluation and align with biomarker strategies for clinical translation
Synthesize and integrate complex biological datasets to inform decision-making across development stages
Select and manage CROs while building strong collaborations to enhance scientific execution and delivery
Present data and program strategies to asset teams, governance committees, and senior leadership
Contribute to key regulatory and scientific documents including INDs, NDAs, study protocols, and publications

Bachelor’s degree in life sciences or a related field
12+ years of experience in translational sciences within a pharmaceutical or biotechnology environment
Deep expertise in neurology drug discovery and preclinical development
Experience supporting clinical-stage development programs
Hands-on experience with regulatory filings including IND, BLA, or NDA
Experience across therapeutic platforms including small molecules, ASO, and mRNA preferred
Proficiency working with complex, multifactorial biological datasets and data analysis platforms
Willingness and ability to travel domestically and internationally as needed

Regular standing, walking, sitting, and the use of hands for handling or operating equipment
Reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations
Occasionally lift and/or move up to 20 pounds
The ability to travel independently overnight and/or work after hours as required by travel schedules or business needs

Competitive base, bonus, new hire and ongoing equity packages
Medical, dental, and vision insurance
Employer-paid life, disability, business travel and EAP coverage
401(k) Plan with a fully vested company match 1:1 up to 5%
Employee Stock Purchase Plan with a 2-year purchase price lock-in
15+ vacation days
13 -15 paid holidays, including office closure between December 24th and January 1st
10 days of paid sick time
Paid parental leave benefit
Tuition assistance

We are committed to building a diverse, equitable, inclusive, and innovative company, and we are looking for the BEST candidate for the job.
Reasonable Accommodation Request Form
Contact Information: talentacquisition@acadia-pharm.com or 858-261-2923

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