Senior Director of Clinical Science - Hematology

Reporting to the Executive Director – Hematology, Oncology Assets and Early Development or the Head of Clinical Science Oncology, this role provides strategic Clinical Science leadership across the hematology disease area, spanning multiple studies, programs, and assets.

Responsibilities

• Provide strategic Clinical Science leadership across the hematology disease area, including multiple studies, programs, and assets.
• Contribute to disease area strategy by applying deep therapeutic expertise in hematologic cancers, including disease biology, current and emerging treatment landscape, relevant clinical endpoints, and key scientific considerations.
• Partner with Section Heads, Asset Leads, Program Development Team Leads, and cross-functional development team members to support study planning, data interpretation, issue resolution, and broader program decisions.
• Lead efforts to standardize Clinical Science approaches, including medical data review practices, data interpretation principles, and key deliverables across the hematology portfolio.
• Promote consistency in Clinical Science activities while allowing for program-specific needs and advocate for innovative approaches such as visual analytics and AI-enabled workflows.
• Provide senior scientific guidance on clinical data interpretation, protocol development, study design, endpoint selection, eligibility criteria, and biomarker strategy discussions.
• Contribute Clinical Science perspective to portfolio discussions, governance reviews, and senior leadership meetings, ensuring sound scientific judgment informs decisions.
• Manage and develop multiple Clinical Scientists, setting clear expectations for scientific quality, strategic thinking, collaboration, and communication.
• Foster a culture of accountability, inclusion, continuous learning, and strong team performance within the Clinical Science team.
• Collaborate closely with Clinical Operations, Regulatory Affairs, Biostatistics, Data Management, Drug Safety, Translational Medicine, Medical Affairs, and other partner functions.
• Ensure Clinical Science activities comply with regulatory requirements, company policies, and established procedures, supporting inspection readiness.
• Identify opportunities to improve the quality, consistency, and effectiveness of Clinical Science work across the hematology disease area.

Requirements

• Advanced scientific or healthcare degree (PhD, PharmD) with at least 7 years of hematological oncology drug development experience, or Master’s Degree in life sciences with 12 years of relevant experience.
• Significant experience in Clinical Development, Clinical Science, or a related function within the pharmaceutical or biotechnology industry.
• Demonstrated leadership across multiple studies, programs, or assets in hematologic cancers, with deep expertise in disease biology, treatment landscape, and clinically relevant endpoints.
• Strong understanding of clinical trial design, development strategy, clinical data review, and interpretation of oncology data.
• Experience contributing to disease area strategy, portfolio discussions, cross-program planning, regulatory submissions, or health authority interactions.
• Proven ability to work effectively in cross-functional, matrixed environments and integrate information across studies to support scientific and business decisions.
• Excellent communication, influence, and executive presentation skills.
• Demonstrated people leadership experience, including management, coaching, and development of scientific staff.

Skills

• Required: Change Agility, Clinical Development, Clinical Oncology, Clinical Reporting, Clinical Research, Clinical Sciences, Clinical Study Management, Clinical Trial Management, Hematology, Medical Sciences, Oncology, People Leadership, Scientific Literacy.
• Preferred: Experience with visual analytics, centralized data review, or AI-enabled workflows in clinical development.

Pay

The salary range for this role is $190,800 to $300,300. An employee’s position within the range will be based on factors including education, qualifications, certifications, experience, skills, geographic location, and business needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Benefits

We offer a comprehensive package of benefits, including medical, dental, vision, and other insurance benefits for employees and their families, as well as retirement benefits.

Travel requirements: 0-25%.