Senior Director, Medical Monitor (Respiratory indications)

The Role

Generate:Biomedicines is seeking an experienced physician for medical oversight of our late-stage Respiratory (asthma and COPD) programs. This individual will report to the Executive Director of Clinical Development and serve as the Senior Director Medical Monitor for Phase 3 global trials, ensuring scientific rigor, patient safety, and executional excellence.

Provide day-to-day medical oversight

• Ensure patient safety, protocol compliance, data integrity, and inspection readiness
• Primary medical contact for clinical sites, investigators, and CROs
• Subject eligibility review, ongoing data reviews, manage study queries, identify and assess protocol deviations

Contributing author and key reviewer

• Core clinical and regulatory documents including IB, ICF, RFI, study protocols, DSUR
• Support study oversight committees including DSMB, endpoint adjudication committee, etc.

Leadership Responsibilities

• Hold teams to high standards for technical and collaborative performance
• Foster a high-performing, diverse, and inclusive team culture
• Promote enterprise thinking and strategic alignment across functions
• Communicate with clarity, courage, and empathy
• Model resilience, adaptability, and informed risk-taking

The Ideal Candidate

• MD (required); board certification in Pulmonology or Allergy & Immunology preferred
• 8+ years of clinical development experience in the biopharma industry
• Extensive expertise in asthma and respiratory clinical trial design, oversight, and execution
• Strong cross-functional leadership and communication skills
• Proven ability to collaborate with internal teams and external stakeholders

Nice to Have

• Experience in both large pharma and biotech settings
• Familiarity with global regulatory frameworks (e.g., FDA, EMA)
• Prior involvement in successful BLA or MAA submissions

About Generate:Biomedicines

We are a clinical-stage generative biology company pioneering the AI revolution in drug design and development. We are advancing a new approach to drug creation—one grounded in the ability to design proteins with defined biological intent. By integrating machine learning with large-scale experimentation, this approach aims to reduce the uncertainty, time, and cost associated with developing protein-based medicines.

Compensation

In addition to a competitive benefits package, you will be eligible for an annual bonus and equity compensation. Per year salary range: $277,000—$400,000 USD.