Senior Director, Global Clinical Development, Neuroscience

Working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, transforming the lives of patients and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. We recognize the importance of balance and flexibility, offering a wide variety of competitive benefits, services, and programs to support both professional and personal goals.

About the role

The Senior Director Global Clinical Development, Neuroscience will serve as the main point of contact to prepare the clinical development plan, design clinical trials, and lead the clinical development teams. This role is part of a global scientific organization dedicated to evaluating new molecules, biomarkers, and mechanistic hypotheses in humans, driving clinical strategy, and selecting promising drug candidates for development.

Responsibilities

• Medical Monitoring
  • Articulate clinical development strategy.
  • Analyze, interpret, and act on clinical trial data to guide development.
  • Serve as principal functional author for regulatory submissions, study reports, and publications.
  • Independently synthesize and contribute to plans (e.g., trial design, development strategy, regulatory strategy) based on data and multi-functional input.
  • Design and develop clinical studies and research plans in support of asset strategy with program and clinical development teams.
• Clinical Development Expertise & Strategy
  • Manage multiple/complex active programs concurrently across clinical lifecycles.
  • Accountable for clinical contribution to the development of indication strategy.
  • Partner with Worldwide Patient Safety physicians in the ongoing review of safety data.
  • Provide clinical leadership and disease area expertise into integrated disease area strategies.
  • Partner closely with Key Opinion Leaders (KOLs) in specific indications.
  • Evaluate strategic options against a given Target Product Profile (TPP).
  • Collaborate with Global Development Operations/Global Compliance Group to develop asset-level risk management plans and resolve quality issues.
  • Set executional priorities and partner with Clinical Scientists to support delivery of studies.
  • Accountable for top-line data with support from Clinical Scientists and Statisticians.
  • Liaise with Clinical Scientists, Translational & Discovery Scientists, and Development Teams to define dose, schedule, indications, and patient selection (e.g., biomarker qualification).
  • Apply foresight and prioritize translational objectives in anticipation of development needs.
  • Ad-hoc involvement in departmental or enterprise initiatives (e.g., committees, sub-teams).
  • Present and articulate clinical strategy to senior leadership to support portfolio progression.
• Health Authority Interactions
  • Serve as primary clinical representative in regulatory interactions.
  • Accountable for clinical contributions to clinical study reports (CSRs), regulatory reports, briefing books, and submission documents.
• External Partnerships, Alliances, and Publications
  • Define and establish relationships with key investigators.
  • Participate in teams responsible for establishing alliances with academic centers, cooperative groups, vendors, and government agencies.
  • Represent the department in business development due diligence and partner alliance management (e.g., JDC/JRC/JSC).
  • Demonstrate a track record or recognition for contributions to the field (e.g., publications, patents, keynote participation).
• Leadership and Matrix Management
  • Manage Clinical Trial Physicians and Clinical Scientists, attracting, developing, and retaining top talent.
  • Ensure appropriate training and mentoring of other physicians and scientists.
  • Champion a quality-focused mindset and ensure adherence to GCP and compliance obligations.

Requirements

• Degree Requirements
  • Advanced degree(s) in a relevant field: MD or MD/PhD with deep clinical expertise in a therapeutic area.
  • Fellowship/specialty training in a relevant therapeutic area preferred.
• Experience Requirements
  • 7+ years of relevant experience in discovery, translational, and/or clinical research in academic or industry settings.
  • Extensive experience in clinical trial design and execution, biomarker development, and development strategy in the pharmaceutical industry.
  • Deep understanding of pharmaceutical discovery, development, and commercialization.
  • Track record of mentorship, management, and/or matrix leadership.
  • Demonstrated leadership abilities in a matrix environment.
• Key Competency Requirements
  • Excellent skills in clinical development strategy, including clinical components of regulatory submissions.
  • External focus to understand trends in disease area treatment paradigms and ability to build relationships with external partners and thought leaders.
  • Ability to partner and interact with colleagues across the development lifecycle.

Skills

• Extensive experience in clinical development of neurodegenerative and/or neuropsychiatric indications (required).
• Demonstrated expertise in basic research related to neurodegeneration and/or neuropsychiatry (a plus).

Pay

Starting compensation ranges (full-time employee basis):

• Cambridge Crossing: $350,780 - $425,060
• Madison - Giralda - NJ: $313,200 - $379,524
• Princeton - NJ: $313,200 - $379,524

Additional incentive cash and stock opportunities may be available based on eligibility. Final compensation will be determined based on demonstrated experience.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life Benefits:
  • Paid Time Off for US Exempt Employees: Flexible time off (unlimited, with manager approval) and 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico, or Rayzebio).
  • Phoenix, AZ, Puerto Rico, and Rayzebio Exempt/Non-Exempt/Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays.
  • Additional time off may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs.
  • Annual Global Shutdown between Christmas and New Year’s Day for all global employees (full and part-time).

Schedule

Domestic and international travel may be required.

On-site Protocol: This role is site-by-design, eligible for a hybrid work model with at least 50% onsite at your assigned facility. Onsite presence is considered essential for collaboration, innovation, productivity, and culture.