Senior Conjugation Scientist
Ultimate Staffing · Fenton, MO · 3 days ago
On-siteScience$85k–$125k/yrFull-time
What You'll Do
- Designing and optimizing chemical conjugation processes for antibodies, proteins, and peptides
- Developing robust protocols for fluorophore, enzyme, and specialty-label attachment
- Leading process transfer activities from R&D into manufacturing
- Optimizing reaction conditions, labeling efficiency, yield, stability, and overall process performance
- Troubleshooting technical challenges and implementing process improvements
- Overseeing lab-scale through production-scale conjugation and purification activities
- Collaborating with analytical, cell culture, purification, quality, and production teams
- Managing project timelines and serving as a technical lead for new product initiatives
- Supporting validation activities, process documentation, and compliance with quality systems
- Presenting project updates and technical findings to leadership
Required Qualifications
- Bachelor's or Master's degree in Chemistry, Biochemistry, Organic Chemistry, or a related scientific discipline
- Experience in protein chemistry, antibody conjugation, bioconjugation, or protein labeling
- Hands-on experience with protein purification techniques such as FPLC, HPLC, SEC, CD, dialysis, and related purification methodologies
- Experience characterizing protein conjugates and analyzing process performance
- Strong problem-solving, troubleshooting, and analytical skills
- Ability to work independently while collaborating across multiple teams
Preferred Experience
- Antibody labeling and fluorescent conjugation expertise
- Process scale-up and technology transfer experience
- Knowledge of chromatography-based purification processes
- Experience supporting regulated environments, SOPs, and quality systems
- Project leadership and mentoring experience