Scientist, Purification, RNA Process Development

We need to output HTML fragment with sections: About the role? The posting includes a purpose statement at start: "At Bristol Myers Squibb, our employees often ask..." That's about company culture. Could be "About the role" or maybe "About the company". The instruction: use

for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). We need to include sections only when posting has real specific content. We have: - Position Summary (could be About the role) - Key Responsibilities (Responsibilities) - Qualifications & Experience (Qualifications) - Compensation Overview (Pay) - Benefits (Benefits) - How We Work (maybe Schedule? Actually schedule not given; but we have work models: site-essential etc. Could be Schedule? Not exactly. Could be omitted if not schedule. The instruction says include Schedule only if posting actually states them. Not present. So we skip Schedule. - Supporting People With Disabilities etc is EEO/legal boilerplate; we should remove. - Candidate Rights etc also boilerplate; remove. - Data Protection etc boilerplate; remove. - Application instructions etc; remove. - Job ID etc: we should not put as heading; fold minor metadata into short

or drop it. So we can include a short

with Job ID maybe. We must preserve all substantive information; do not invent or summarize away detail. Remove boilerplate. Thus sections:

About the role

with the position summary paragraph(s). The position summary includes: "Position Summary The RNA Purification Process Development function plays a central role...". Also earlier paragraph about purpose-driven culture maybe part of About the role? Could be included. We need to not repeat job title as heading. So we will not include heading for Scientist, Purification, RNA Process Development. We'll include a short

for metadata: maybe "Job ID: R1606906". But instruction: do NOT put Job ID / requisition numbers as headings — fold minor metadata into a short

or drop it. So we can include a

with that. Now Responsibilities: list bullet points from Key Responsibilities. Qualifications: list bullet points from Qualifications & Experience. Pay: Compensation Overview includes salary range and description. We'll put in

Pay

with paragraphs. Benefits: Benefits section includes description. We'll put

Benefits

. We must not include sections with filler like "commensurate with experience". Not present. We need to ensure we use

• for any list of duties/requirements/benefits. For benefits, we have a paragraph describing benefits; could also list bullet points but not required. We'll keep as

  for prose. We must not include markdown fences. Let's craft. First, maybe a short

  for metadata: "Job ID: R1606906". Could also include location? Not needed. Now About the role: combine the introductory purpose-driven culture paragraph and Position Summary. Let's extract: Intro: "At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it." Position Summary: "Position Summary The RNA Purification Process Development function plays a central role in designing efficient, robust, and scalable manufacturing processes. By combining deep scientific expertise with enabling technologies and strong cross-functional partnerships, RNA Process Development delivers transformative innovation across the pipeline. The Scientist executes robust experiments for drug substance programs spanning early- to late-stage development across circular and linear mRNA modalities. Reporting to the Principal Scientist, this role encompasses hands-on contributions, addressing critical challenges by driving sound experimental execution and manufacturing support. The candidate should be driven by developing and characterizing chromatography and filtration steps for improving the yield, quality and robustness of purification process steps." We'll combine into a few paragraphs. Now Responsibilities bullet list: - Design, execute, and analyze experiments for existing and novel process modes using DoE and statistical modeling - Define the RNA drug substance purification process, the critical parameters, and the design space - Experiment using high throughput/automated or data rich experimental setups - Design experiments to confirm robust process performance across the control space - Collaborate with analytical teams to enable deeper characterization of RNA properties and impurity profiles - Collaborate closely with upstream PD to characterize IVT feed stream to maximize RNA yield and purity - Prepare technical reports, and communicate findings internally and externally as appropriate - Participate in tech transfer activities to GMP manufacturing sites for RNA programs Now Qualifications bullet list: - Degree in Bio/Chemical Engineering, Bio/Chemistry, or related field - BS with 6+ years’ experience in science related disciplines - MS with 4-6 years’ experience in science related disciplines - PhD with 0 - 2 years’ experience in science related disciplines - Expertise in chromatography, filtration (TFF/UF-DF), and innovative separation unit operations - Solid knowledge foundation of statistical design of experiments (DoE) and analysis of multivariate data - Experience with performing process analytics and biophysical characterization techniques such as HPLC, CE, & gel electrophoresis - Knowledge of cGMP, ICH, regulatory guidelines and QbD principles as they apply to risk management and clinical manufacturing - Demonstrated background of providing technical support for clinical manufacturing processes, including support of process investigations, and implementation of proactive process modifications - Knowledge of advanced mathematics, nucleic acid chemistry, lipid chemistry, and biology is a plus - Knowledge of establishing and qualifying scale down models and mechanistic models for process characterization is a plus Also note: "We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway." This is substantive; we could include as a paragraph under Qualifications or maybe a separate section like "Additional notes". But instruction: only include sections when posting has real specific content. Could add a paragraph under Qualifications after list. Now Pay: Compensation Overview paragraph(s): "Compensation Overview Cambridge - MA - US: $110,810 - $134,281 The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance." We'll put as

  Pay

  with

  . Benefits: Benefits paragraph: "Benefits Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays. Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day. U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits" We'll put as

  Benefits

  with

  . We should not include How We Work etc because not requested headings; but could be considered as Schedule? Not exactly. The instruction says include Schedule only if posting actually states them. Not present. So we skip. Now we need to output only HTML fragment, no /. We'll start with maybe a

  for metadata then sections. Let's craft:

  Job ID: R1606906

  About the role

  At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

  The RNA Purification Process Development function plays a central role in designing efficient, robust, and scalable manufacturing processes. By combining deep scientific expertise with enabling technologies and strong cross-functional partnerships, RNA Process Development delivers transformative innovation across the pipeline. The Scientist executes robust experiments for drug substance programs spanning early- to late-stage development across circular and linear mRNA modalities. Reporting to the Principal Scientist, this role encompasses hands-on contributions, addressing critical challenges by driving sound experimental execution and manufacturing support. The candidate should be driven by developing and characterizing chromatography and filtration steps for improving the yield, quality and robustness of purification process steps.

  Responsibilities

  • Design, execute, and analyze experiments for existing and novel process modes using DoE and statistical modeling
  • Define the RNA drug substance purification process, the critical parameters and design space
  • Experiment using high throughput/automated or data rich experimental setups
  • Design experiments to confirm robust process performance across the control space
  • Collaborate with analytical teams to enable deeper characterization of RNA properties and impurity profiles
  • Collaborate closely with upstream PD to characterize IVT feed stream to maximize RNA yield and purity
  • Prepare technical reports and communicate findings internally and externally as appropriate
  • Participate in tech transfer activities to GMP manufacturing sites for RNA programs

  Qualifications

  • Degree in Bio/Chemical Engineering, Bio/Chemistry, or related field
  • BS with 6+ years’ experience in science related disciplines
  • MS with 4-6 years’ experience in science related disciplines
  • PhD with 0 - 2 years’ experience in science related disciplines
  • Expertise in chromatography, filtration (TFF/UF-DF), and innovative separation unit operations
  • Solid knowledge foundation of statistical design of experiments (DoE) and analysis of multivariate data
  • Experience with performing process analytics and biophysical characterization techniques such as HPLC, CE, & gel electrophoresis
  • Knowledge of cGMP, ICH, regulatory guidelines and QbD principles as they apply to risk management and clinical manufacturing
  • Demonstrated background of providing technical support for clinical manufacturing processes, including support of process investigations, and implementation of proactive process modifications
  • Knowledge of advanced mathematics, nucleic acid chemistry, lipid chemistry, and biology is a plus
  • Knowledge of establishing and qualifying scale down models and mechanistic models for process characterization is a plus

  We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to