Scientist - Medicinal Chemistry

About the Role

In this vital role you be part of an innovative Medicinal Chemistry group with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development. This will also include the opportunity to work within Amgens Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. This is an onsite laboratory position at our Thousand Oaks, CA site.

Responsibilities

• Work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry teams, including troubleshooting of synthetic routes and reactions, scouting of new synthetic routes and performing high difficulty synthetic chemistry
• Contribute to the design of new compounds and the development of structure-activity relationships
• Perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of techniques
• Recognized as a lab leader and demonstrate excellent verbal and written communication skills
• Maintain laboratory notebooks, participate in group and project meetings and, as needed, presenting to groups and aiding in the writing of papers and patent applications

Basic Qualifications

• Doctorate Degree
• Masters degree and 2 years of laboratory experience OR
• Bachelors degree and 4 years of laboratory experience

Preferred Qualifications

• Track record of accomplishments (e.g., peer-reviewed publications)
• Demonstrated ability to scout and troubleshoot synthetic routes, and perform high difficulty synthetic chemistry
• Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods
• Demonstration of good lab practices, with particular attention to safety
• Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams

Benefits

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible