Scientist, Medicinal Chemistry

Pay 60-80/h depending on experience Scientist, Medicinal Chemistry We are seeking a motivated, enthusiastic synthetic/medicinal chemist to support preclinical stage programs in the portfolio and make transformative medicines for patients with brain diseases. In this role, the successful candidate will be responsible for working with project teams to design and synthesize first-in-class small molecules and progress them to the drug candidate stage. Essential Functions: Contribute to multi-disciplinary project teams in developing innovative, high-quality small molecule therapeuticsIndependently and with a team design drug-like compounds for synthesis, in line with project strategy, incoming data, and knowledge of in vitro and in vivo DMPK and physicochemical propertiesEmploy state-of-the-art techniques and synthetic methods to design, execute, optimize, and analyze multi-step synthetic strategiesInteract directly with Contract Research Organizations (CROs)Identify opportunities to access state-of-the-art chemistry capabilities and infrastructure, and maintain lab instrumentation Contribute to objective setting for project team Train/mentor associate scientists, research associates, and internsResponsible for data analysis, preparation of reports, and presentations to project teams, site, and global scientific leadershipContribute to publications in peer-reviewed journals, present work at scientific conferences, and prepare patent applicationsApproximately 90% of work is lab-based and focuses on development and execution of synthetic strategies towards drug-like small molecule compounds Required Education, Experience, and Skills: Ph.D. in organic chemistry or related area, or MS with 9+ years experience or a BS with 12+ years experienceDemonstrated broad knowledge of and experience in planning, developing, and enabling multistep organic synthesesExpertise in developing new transformations and in analyzing and optimizing reactionsInnovative, rigorous, and can devise and execute successful synthetic chemistry strategiesAbility to develop, implement, and clearly communicate chemistry strategies to team, management, and collaboratorsExcellent collaboration, communication, and presentation skills.Both effective team player and strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results under tight timelinesThrives in a team environment of shared goals and responsibilities Preferred Education, Experience, And Skills: Experience in medicinal chemistry or pharmaceutical drug discovery/developmentHPLC/UPLC - MS analytical and preparative-scale chromatography experience Expertise in cheminformatics systems and methodsFamiliarity working with Contract Research OrganizationsExperience with hit triage, hit-to-lead chemistry, parallel synthesis, and tool identification Scientist, Medicinal Chemistry We are seeking a motivated, enthusiastic synthetic/medicinal chemist to support preclinical stage programs in the portfolio and make transformative medicines for patients with brain diseases. In this role, the successful candidate will be responsible for working with project teams to design and synthesize first-in-class small molecules and progress them to the drug candidate stage. Preferred Education, Experience, And Skills: Experience in medicinal chemistry or pharmaceutical drug discovery/developmentHPLC/UPLC - MS analytical and preparative-scale chromatography experience Expertise in cheminformatics systems and methodsFamiliarity working with Contract Research OrganizationsExperience with hit triage, hit-to-lead chemistry, parallel synthesis, and tool identification