Scientist l - LBA (Ligand Binding Assay) Ops
About the role
We are seeking an independent, knowledgeable, and highly motivated Ligand Binding Assay Scientist (Scientist I) to join the Quantitative Translational and ADME Sciences (QTAS) department at AbbVie Bioresearch Center in Worcester, MA.
Responsibilities
- Analyze samples by ligand binding assays (PK, PD, TK, ADA) using Meso Scale Discovery platform and colorimetric ELISA or other assay platforms.
- Plan and execute sample analysis based on bioanalytical protocols and in vivo study designs on a variety of biological matrices (tissue lysates, serum, others) from a variety of species (monkey, mouse, rat).
- Analyze pre-clinical in vivo samples based on a dynamically changing operational schedule.
- Imperttut, present, and discuss assay results; use results to guide analysis and adjust strategy.
- Report, discuss, and QC’ing results to project teams which enable pharmacokinetic and pharmacodynamic analysis in support of oncology, immunology, neurology, and other AbbVie therapeutic portfolios.
- Communicate experimental plans and results effectively, both verbally and in writing during regular lab meetings and with broader teams.
- Independently and efficiently initiate, design, interpret, and troubleshoot operational assays.
Qualifications
- Bachelor’s degree in biology, biochemistry, pharmacology, or related field with at least 5 years of pharmaceutical experience or MS in mentioned fields with 2+ years of relevant experience.
- Experience with ligand binding workflow and assay development and troubleshooting is required.
- Strong attention to detail, with demonstrated impact as an independent and self-motivated contributor.
- Ability to operate and maintain laboratory equipment and reagents/material inventories independently.
- Experience with lab automation is desirable.
- Proven independence and problem-solving ability.
- Excellent written and verbal communication skills and ability to draft technical reports.
- Proficiency with computers and data analysis/documentation software including Excel, LIMS, and ELN.
- Ability to summarize, communicate, and interpret bioanalytical results.
- Ability and willingness to work effectively in a highly collaborative and multidisciplinary environment.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html. US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html.