Biomarkers Research Lab Scientist (Ligand Binding Assays)
About the role
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. Our teams bring together deep scientific expertise, advanced technologies, and a commitment to improving patient outcomes through discovery, development, and delivery of innovative therapies. Within Vertex, the Biomarkers organization plays an important role in advancing clinical development through biomarker research, assay development, and cross-functional collaboration. Vertex is seeking a hands-on Biomarkers Research Lab Scientist to develop and optimize biomarker assays that support clinical trials at Vertex. This individual will design and execute experiments to characterize novel biomarkers in human biofluids and tissues. This role offers the opportunity to contribute to innovative clinical biomarker studies while collaborating closely with members of the Biomarkers lab team and, as needed, with Research, Quality, and Biomarker Leads. The ideal candidate brings strong laboratory experience, effective communication skills, and a collaborative approach.
Responsibilities
- Develop innovative biomarker assays for clinical studies at Vertex through hands-on laboratory work
- Characterize biomarkers in human biofluids and tissues and evaluate assay feasibility
- Perform mock validation experiments and contribute to the generation of data packages supporting assay readiness
- Partner with members of the biomarkers group to support assay transfer to CROs and external laboratories, including technical handoff and troubleshooting
- Analyze, interpret, and present experimental results to internal stakeholders and project teams
Requirements
- Ph.D. or equivalent degree with 0–3 years of relevant post-doctoral employment experience, or
- Master’s degree or equivalent degree with 3+ years of relevant employment experience, or
- Bachelor’s degree or equivalent degree with 6+ years of relevant employment experience
- Hands-on experience developing ligand binding assays for translational or clinical applications
- Strong laboratory experience in molecular biology and cell biology
- Effective communication and interpersonal skills, with proven ability to work effectively as a member of a multidisciplinary team
- Method development and validation experience in ligand binding assays