Scientist, In Vivo Pharmacology

Working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, transforming the lives of patients and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment, offering a wide variety of competitive benefits, services, and programs that provide employees with resources to pursue their goals.

About the role

The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. The team is committed to discovering and developing transformative therapies that improve patient outcomes.

Bristol Myers Squibb is seeking a highly motivated Scientist to join the In Vivo Pharmacology group supporting Oncology and Immunology discovery programs. The successful candidate will play a key role in the design, execution, analysis, and interpretation of preclinical in vivo studies to evaluate novel therapeutic candidates. This position requires a strong scientific background in pharmacology, immunology, and/or oncology, as well as the ability to independently drive experimental strategies and collaborate within multidisciplinary discovery teams.

Responsibilities

• In Vivo Study Execution (Oncology & Immunology)
  • Design and interpret in vivo studies in murine models of cancer and immune-mediated diseases.
  • Perform and oversee in vivo studies, including compound administration, disease induction, tumor implantation, immune cell transfers, longitudinal sampling, and animal monitoring.
  • Develop experimental strategies to evaluate pharmacodynamic, efficacy, mechanism-of-action, and combination therapy hypotheses.
  • Independently operate and apply imaging technologies, including IVIS, to support efficacy and mechanistic studies.
  • Troubleshoot technical and scientific challenges and develop solutions to improve study outcomes.
  • Contribute to the optimization and development of novel in vivo models and experimental workflows.
• Data Analysis & Reporting
  • Analyze and interpret complex datasets using GraphPad Prism, Excel, and other data analysis tools.
  • Integrate in vivo, pharmacodynamic, biomarker, and mechanistic data to generate actionable scientific insights.
  • Maintain accurate and timely electronic laboratory notebook (ELN) documentation.
  • Prepare and present study results, scientific reports, and project updates to cross-functional teams and leadership.
  • Contribute to scientific publications, technical reports, presentations, and regulatory documentation as appropriate.
• Cross-Functional Collaboration
  • Serve as an in vivo pharmacology representative on Oncology and Immunology project teams.
  • Partner with external collaborators and contract research organizations (CROs) to support study execution and data interpretation.
  • Contribute scientific insights to project strategy, portfolio discussions, and candidate advancement decisions.
• Laboratory Operations & Compliance
  • Ensure compliance with BMS policies, IACUC regulations, and animal welfare standards.
  • Maintain lab supplies, equipment, and study materials.
  • Participate in continuous improvement of in vivo models and workflows.

Requirements

• Basic Qualifications
  • Bachelor’s Degree and 5+ years of academic and/or industry experience
  • OR Master’s Degree and 3+ years of academic and/or industry experience
  • OR Ph.D. or equivalent advanced degree in the Life Sciences (no experience necessary)
• Preferred Qualifications
  • PhD in Pharmacology, Immunology, Oncology, Cell Biology, or a related life science discipline; or MS with 3+ years, or BS with 5+ years of relevant industry experience in in vivo pharmacology.
  • Strong scientific expertise in preclinical in vivo pharmacology.
  • Demonstrated experience designing, executing, and interpreting studies in oncology and/or immunology disease models.
  • Hands-on experience with rodent handling, dosing techniques, and biological sample collection.
  • Experience with tumor models, immune-mediated disease models, or both.
  • Proficiency with IVIS imaging and associated data analysis.
  • Strong understanding of experimental design, statistics, and data interpretation.
  • Excellent problem-solving skills and scientific curiosity.
  • Strong written and verbal communication skills with the ability to effectively present scientific findings.
  • Ability to manage multiple priorities and work effectively in a collaborative, fast-paced research environment.
  • Industry experience in biotech or pharmaceutical R&D desired.
  • Experience working in matrixed, cross-functional teams desired.
  • Familiarity with imaging techniques, biomarkers, or molecular assays desired.

Pay

Cambridge, MA, US: $128,380 - $155,571. The starting compensation range is for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account required skills, job location, work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life Benefits:
  • Paid Time Off for US Exempt Employees: flexible time off (unlimited, with manager approval), 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico, or Rayzebio employees).
  • Phoenix, AZ, Puerto Rico, and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays.
  • Additional time off for eligible employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs, and an annual Global Shutdown between Christmas and New Year’s Day.

Schedule

This role follows an on-site protocol with the following occupancy structure:

• Site-essential roles require 100% of shifts onsite at your assigned facility.
• Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. Onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive company culture.