Scientist III

Job Summary Looking to take your downstream purification expertise to the cutting edge of RNA and peptide therapeutics? Join our Cambridge team to hands-on design, characterize, and scale up novel purification processes. In this role, you will evaluate innovative technologies, lead pilot-scale initiatives, and directly support clinical and commercial manufacturing programs that impact patient lives. location: Cambridge, Massachusetts job type: Contract salary: $49 - 54 per hour work hours: 9 to 5 education: Bachelors Responsibilities Investigate new purification technologies that seek to enhance purity, process robustness and/or Develop and characterize purification processes for a rapidly expanding pipeline of new oligonucleotides and peptide drug therapies.The individual will utilize multiple modes of chromatography and ultrafiltration and learn chemical cleavage/conjugation/hybridization steps. productivity of our existing oligonucleotide platform process. Collaborate cross-functionally with other groups to improve process understanding and manage team activities.Document laboratory work in development reports, training/mentoring of new employees, and lead pilot scale activities.Scale-up and technology transfer oligonucleotide processes into our pilot and GMP manufacturing facilities and participate in writing regulatory sections for INDs. Qualifications Required: Bachelor's degree in Biochemistry, Chemical Engineering, Chemistry, or related life science field with 2-4 years industry experience (or master's degree with 0-2 years of industry experience).Proven record of successfully planning and executing projects and experiments.Lab experience in purification of proteins, peptides and/or DNA/RNA using column chromatography (e.g., Ion exchange, Hydrophobic Interaction, and/or Reversed phase) and UF/DF.Some hands-on experience in analysis of proteins, peptides or DNA/RNA, preferably using both HPLC and UV/Vis spectroscopy.Demonstrated technical proficiency and creativity in developing innovative technologies/approaches in purification.Excellent organizational, verbal and written communication, and time management skills. Preferred Experience using AKTA purification systems and Unicorn software and use of statistical design (DoE).Experience in statistical analysis. skills: Chemistry, High Pressure Liquid Chromatography (HPLC), Good Laboratory Practices (GLP), Investigational New Drug (IND), Chemistry Manufacturing and Controls (CMC) Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status. At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact HRsupport@randstadusa.com. Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility). This posting is open for thirty (30) days. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. u00006475229