Scientist I - RNA Therapeutic Discovery (6-month contract)

Job Responsibilities

• Design, execute, and interpret experiments to improve therapeutic performance of designer RNA molecules
• Support research activities that contribute to the company's intellectual property portfolio
• Interpret data, generate figures, and clearly communicate findings to the team
• Maintain accurate and detailed records using ELN

Skills/Capabilities

• Extensive hands-on experience with mammalian cell culture, particularly iPSCs and iPSC-derived cell models
• Proven expertise in working with AAV vectors, including handling, titration, and transduction in challenging cell types (e.g., iPSC-derived cells)
• Proficiency with basic molecular biology techniques: plasmid design, cloning, primer design and PCR, DNA isolation, gel electrophoresis, Sanger sequencing analysis
• Proficiency with RNA extraction and quantification by qPCR and ddPCR
• Protein extraction and western blot
• Eagerness to learn and receptive to feedback
• Demonstrated problem solving and troubleshooting skills

Requirements

• Ph.D. in molecular/cellular biology, biochemistry, genetics, or related field with 5+ years relevant laboratory experience
• Background in RNA, muscle biology, cardiac biology, and/or neuroscience