Scientist (6 Month Contract) – High Throughput Biophysics - TR-FRET

Principal Duties and Responsibilities

• Design, develop and implement a variety of kinetic-focused, protein-protein interaction/degradation assays in low and high-throughput settings.
• Standard assays include TR-FRET, FP, DSF, DLS, and SPR.
• Screen and characterize small molecule compounds and determine the mode of action.
• Experience in handling and QCing recombinant protein.
• Standard assays include DSF/DLS, FIDA, and analytical SEC.
• Analyze and interpret integrated datasets.
• Maintain laboratory records, protocols, and summaries.
• Contribute to laboratory organization and maintenance.
• Present research plans and results, both within the team and to senior management.

Qualifications

• BS/MS with at least 2 years pharma/biotech drug discovery laboratory experience in screening.
• Skill in biochemical and biophysical assays and recombinant protein.
• Experience with various compound screening formats, laboratory instrumentation, and high throughput automation.
• Experience with sample management processes and instrumentation.
• Proven ability to work independently and design experiments, troubleshoot, interpret and report large datasets.
• A highly analytical mind, attention to detail and organization skills are critical.