Scientist I, DMPK / ADME

About the role

Conduct routine in vitro ADME assays in compliance with applicable methods, including weighing chemicals, preparing solutions, performing assays, and generating data reports to support discovery and development programs in DMPK.

Responsibilities

• Perform routine in vitro ADME assays, laboratory techniques, and procedures under supervision.
• Receive specific instructions on assigned tasks and expected results.
• Deliver accurate results on assigned tasks within the expected timeframe.
• Follow ADME assay acceptance criteria.
• Understand the study and method; assist in troubleshooting unexpected results.
• Maintain research notebooks in a well-organized manner, ensuring all necessary documentation is recorded.
• Prepare various types of solutions used in the laboratory.
• Perform routine calculations; tabulate and record results.
• Prepare accurate routine data summaries under supervision.
• Maintain and calibrate laboratory equipment and support necessary laboratory supply.
• Comply with SOPs, guidelines, and good housekeeping policies.
• Learn and enhance technical knowledge of in vitro ADME assays (e.g., stability, CYP inhibition/induction, and transporter) and DMPK (e.g., ADME, PK, Metabolism, and bioanalysis).
• Follow company policies, including safety policies, practices, and procedures, to maintain a safe work environment.
• Work weekend hours when necessary and extended hours when project requires.
• Perform other duties as assigned.

Requirements

• Bachelor’s degree in Chemistry, Biology, or a related science field with 0-3 years of experience, or an equivalent combination of education and/or work experience.
• Associate’s degree with 2-3 years of related experience, or an equivalent combination of education and/or work experience.

Skills

• Basic understanding of scientific discipline.
• Ability to perform preliminary lab work with supervision after training.
• Ability to follow instructions to perform required procedures.
• Knowledge of commonly used concepts, practices, and procedures within drug discovery and development R&D laboratory settings.
• Well-organized, detail-oriented, and adaptable to changes.
• Good oral and written communication and interpersonal skills.
• Computer skills: proficiency in internet research, MS Word, Excel, Outlook, and PowerPoint.
• Good time management skills to handle multiple projects within timelines.
• Ability to work in a team environment.
• Ability to follow and adhere to non-GLP guidelines/SOPs consistent with WuXi AppTec requirements.

Schedule

Position includes weekend hours when necessary and extended hours when project requires.