Scientist I - ADME Tox
Eurofins · St Charles, MO · 1 wk ago
AnalystFull-time
About the role
Eurofins Scientific is an international life sciences company providing analytical testing services across industries. The Scientist I will support the Eurofins Discovery business in contract research services, requiring applied experience in analytical chemistry method development and analysis, preferably in a CRO or industry laboratory.
Responsibilities
- Perform work in a laboratory setting and meet the physical job requirements of a lab role.
- Provide leadership and mentorship for junior scientists, and lab leadership through daily lab management, equipment management and lab planning.
- Develop Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/DMPK and BioAnalysis applications.
- Develop analytical methods supporting project teams both internally and externally for new assay development.
- Perform troubleshooting and maintenance of mass spectrometers and HPLC units.
- Experience with Sciex® or Thermo High Resolution/Accurate Mass Instrumentation is a plus.
- Prepare and manage inventory of buffers, reagents, semi-finished and finished goods.
- Provide solutions to more complex problems, identify and initiate process improvements.
- Perform data and report QC review within the department and may support the Study Director.
- Support validation of new methods that contribute to expansion of service/product line, equipment, and data management systems.
Qualifications
- 3+ years of direct/demonstrated experience with Liquid Chromatography- Mass Spectrometry (LC-MS) in a contract research organization or industry laboratory in one or more of the following areas:
- Bioanalytical Method Development for Small and/or Large Molecules
- Drug Metabolism and Metabolite Identification w/ Structural Elucidation
- Mass Spectrometry-Based Proteomics experimental design & execution
- Demonstrated experience with validation of bioanalytical methods in accordance with regulatory (FDA, ICH, OECD) guidelines.
- Experience working in a Quality Management System.
- Demonstrated proficiency in High-Throughput analytical method development for small molecules.
- Experience in leading and delivering results in R&D or innovation programs.
- Demonstrated experience leading in human mammalian cell culture laboratories.
- Demonstrated experience working with light-based readers with 384-well and 96-well plates.
- B.S. with 3 years of relevant experience, M.S. with 2 years of relevant experience, Ph.D. with 1 year of relevant experience, or an equivalent combination of education and experience.
- Ability to work in the U.S. indefinitely without sponsorship or restriction.
Benefits
- Excellent full time benefits including comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
Schedule
The position is full-time, Monday‑Friday, 8 a.m.–5 p.m., with overtime as needed.