Scientist I - Brain Science Management

About the role

The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through the integration of experiments, modeling, and theory.

The Brain Science Management department, led by Hongkui Zeng, seeks to hire an exceptional individual who will carry out research projects investigating the roles of cell types and circuits in mediating innate and social behaviors or the effects of psychoactive drugs in mice.

Responsibilities

• Independently plan experiments (including single-cell genomics, spatial transcriptomics, circuit tracing, animal behavior, etc.), coordinate with pipeline core and resource teams to conduct the experiments, organize the data and analyze the results
• Analyze large-scale single-cell genomics data, utilizing existing and adopting new computational approaches
• Participate in and support other team-based projects, through data sharing and joint analysis
• Maintain clear and accurate communications with supervisor, team members, and external collaborators
• Present a periodic summary of progress to internal and external research community
• Publish and present findings in peer-reviewed journals and scientific conferences

Requirements

• Ph.D. in Neuroscience, Genomics, Molecular Biology, or related field; or equivalent combination of degree and experience
• Proven strong publication record
• Experimental experience and knowledge in mouse genetics
• Solid understanding of the principles of nervous system cell types and neuroanatomy
• Experience in single-cell transcriptomics and epigenomics data generation and analysis
• Proficiency in Python and/or R

Preferred

• Advanced knowledge and experience with cutting-edge experimental techniques such as single-cell transcriptomics, spatial transcriptomics and/or viral-based circuit tracing techniques
• Skilled at adopting new computational (including AI/ML) approaches
• Experience in developing, testing, implementing, and sharing new experimental paradigms quickly, and managing multiple projects efficiently
• Excellent oral and written communication and organizational skills
• Ability to work independently and within a collaborative, multi-disciplinary environment to meet aggressive timelines
• Positive attitude, self-starter, demonstrated attention to detail, and ability to trouble-shoot

Work Environment

• Working at a desk with computer analyzing data
• Laboratory atmosphere - possible exposure to chemical, biological or other hazardous substance
• Exposure to BioSafety Level 2 materials, such as recombinant viruses
• Exposure to and handling of laboratory animals
• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment

Position Type/Expected Hours of Work

This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N.

Travel

• Occasional travel to collaborator sites
• Occasional attendance and participation in national and international conferences may be required

Additional Eligibility Qualifications

• All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on your health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Additional Comments

Please note, this opportunity offers relocation assistance

Please note, this opportunity does not offer visa sponsorship