Scientist - High-Throughput Screening & Analytical Chemistry

Responsibilities

• Develop and optimize analytical methods for targeted metabolite quantification
• Lead method development on GC/MS, GC-FID, and LC-QQQ-MS platforms
• Design high-throughput analytical workflows with fast cycle times
• Develop sample preparation and derivatization strategies
• Work with automation and screening teams to support microtiter plate-based fermentations
• Analyze and interpret large datasets
• Mentor junior staff
• Interface with instrument vendors to maintain uptime and optimal performance
• Author SOPs and technical reports

Qualifications

• PhD in Analytical Chemistry, Chemistry, or related field OR MS with 8+ years of relevant experience
• Strong experience in analytical method development
• Required technical expertise in GC-FID and GC/MS assay development for targeted quantitation and metabolite profiling, LC/QQQ-MS assay development for targeted quantitation, assay optimization for speed, sensitivity, and throughput
• Preferred experience includes integration of analytical workflows with automation, familiarity with liquid handling platforms, experience with LIMS (e.g. Benching), large datasets, industrial biotech or applied R&D experience, experience with specific analytical instrumentation (UHPLC, GC-FID, GC/MS, LC/QQQ-MS), and experience with various sample extraction and preparation techniques, applying automated solutions when appropriate, from complex matrices (microbial fermentation broth, microbial biomass, purified extracts)