Scientist, Cell Line Development

Role Overview

Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes. Your Role: As a Cell Line Development Scientist, you will play a critical role in establishing high-performing mammalian cell lines that enable early-phase biologics programs.

Design and Execution

• Design and execute strategies for stable cell line development using CHO cell line systems.
• Perform hands-on CHO cell line development and characterization studies, including transfection, selection, single cell subcloning, growth and productivity screening, cell banking and stability assessment of cell banks.
• Culture mammalian cells across multiple scales and formats, from 96-well plates up to large shake flasks, experience with ambr 250 and bioreactors is ideal.
• Implement high-throughput screening and automation tools for clone evaluation.

Documentation and Compliance

• Maintain rigorous documentation and ensure compliance with quality and regulatory standards.
• Author and review cell line development reports, summaries, and presentations.

Collaboration and Integration

• Present updates at client and cross-functional meetings.
• Partner with Upstream and Downstream Process Development and Analytical teams to deliver integrated solutions.
• Contribute to technology evaluations and continuous improvement initiatives for cell line workflows.

Qualifications

• M.S. in Cell Biology, Molecular Biology, Biochemistry, or related field.
• 2-5 years of industry experience in cell development for biologics.
• Hands-on experience with CHO cell systems, transfection methods, and clone screening for production of monoclonal antibodies, antibody-like molecules, enzymes, cytokines, bi-specifics and other recombinant molecules.
• Strong knowledge of mammalian cell culture, molecular biology techniques and bio process engineering concepts.
• Proficient in aseptic mammalian cell culture techniques.
• Familiarity with automation platforms and data analysis tools.
• Excellent problem-solving and communication skills.

Preferred Qualifications

• Knowledge of regulatory requirements for GMP manufacturing.
• Exposure to high-throughput analytics and bioinformatics tools.

Position Details

• Position Type/Expected Hours of Work: Full-time, Monday through Friday. Overtime and weekend work may be required.

Compensation

• The compensation range for this role is $85,000 to $116,000 annually depending on experience and qualifications.
• We offer competitive compensation packages, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.

Who You Are

• You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
• Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
• You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
• You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.

Physical Demands & Work Environment

• In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 20 pounds.
• The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally.
• Reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting.